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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-12</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>14.00.00 МЕДИЦИНСКИЕ НАУКИ</subject></subj-group></article-categories><title-group><article-title>ИНТЕНСИВНОСТЬ СОСУДИСТОГО ВОСПАЛЕНИЯ У ПАЦИЕНТОВ С АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ НА ФОНЕ ПРОВОДИМОЙ ТЕРАПИИ</article-title><trans-title-group xml:lang="en"><trans-title>INTENSITY OF VASCULAR INFLAMMATION AT PATIENTS WITH ARTERIAL HYPERTENSION AGAINST PERFORMED THERAPY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Елыкомов</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Elykomov</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костюченко</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostyuchenko</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">gkostyuchenko@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вьюн</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Viun</surname><given-names>O. G.</given-names></name></name-alternatives><email xlink:type="simple">caducei_22@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костюченко</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostyuchenko</surname><given-names>L. A.</given-names></name></name-alternatives><email xlink:type="simple">lilya.kostyuchenko@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России; КГБУЗ «Алтайская краевая клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SBEI HPE «Altai State Medical University» of the Ministry of Health; RSBHE «Altai regional clinical hospital»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>КГБУЗ «Алтайская краевая клиническая больница»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RSBHE «Altai regional clinical hospital»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФКГУЗ «Медико-санитарная часть МВД России по Алтайскому краю»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FRSHE «Medicosanitary hospital of the Ministry of Internal Affairs of Russia in Altai Krai»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ГБОУ ВПО «Алтайский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SBEI HPE «Altai State Medical University» of the Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>1</issue><fpage>11</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Елыкомов В.А., Костюченко Г.И., Вьюн О.Г., Костюченко Л.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Елыкомов В.А., Костюченко Г.И., Вьюн О.Г., Костюченко Л.А.</copyright-holder><copyright-holder xml:lang="en">Elykomov V.A., Kostyuchenko G.I., Viun O.G., Kostyuchenko L.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/12">https://jsms.elpub.ru/jour/article/view/12</self-uri><abstract><p>Цель исследования. Провести сравнительное изучение уровней маркеров сосудистого воспаления в сыворотке крови у пациентов с артериальной гипертензией на фоне гипотензивной терапии. Материалы и методы. Обследовано 120 мужчин (средний возраст 33,4 ± 2,9 года) с верифицированным диагнозом артериальной гипертензии, получавших стандартную антигипертензивную терапию (лозартан). Определяли в сыворотке крови: концентрацию глюкозы и фракций холестерина (ТГ, ЛПВП, ЛПОНП, ЛПНП), эндотелина-1, гомоцистеина и вчСРБ. Результаты. Выявлены достоверно более высокие уровни ГЦ и вчСРБ в сыворотке крови у пациентов с недостигнутыми уровнем АД по сравнению с группой пациентов, у которых уровень АД на фоне гипотензивной терапии достиг целевых значений. Заключение. Полученные нами результаты свидетельствуют о сопряженности интенсивности сосудистого воспаления и эффективности гипотензивной терапии.</p></abstract><trans-abstract xml:lang="en"><p>The objective of research is to carry out comparative studying of levels of markers of vascular inflammation in blood serum at patients with arterial hypertension against hypotensive therapy. Materials and methods . 120 men (middle age was 33,4 ± 2,9 years) with verified diagnosis of arterial hypertension receiving standard anti-hypertensive therapy (losartan) are examined. The following data was defined in blood serum: concentration of glucose and fractions of cholesterol (TG, HDL, VLDL, LDL), endothelin-1, homocysteine and chCRP. Results . The more HC high levels and chCRP in blood serum at patients with unachieved AH level in comparison with group of patients at whom the AH level against hypotensive therapy reached target values are registered. Conclusion . The received results testify to associativity of intensity of vascular inflammation and efficiency of hypotensive therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>артериальная гипертензия</kwd><kwd>сосудистое воспаление</kwd><kwd>эндотелин-1</kwd><kwd>гомоцистеин</kwd><kwd>вчСРБ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial hypertension</kwd><kwd>vascular inflammation</kwd><kwd>endothelin-1</kwd><kwd>homocysteine</kwd><kwd>chCRP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Al-Kirwi E. N. Hypertension and obesity in relation to high sensitivity C-reacive protein and lipid profile in iraqi patients / E. N. Al-Kirwi, A. A. Baydaa // Journal of Al-Nahrain University. - 2009. - N 12. - Р. 145-150.</mixed-citation><mixed-citation xml:lang="en">Al-Kirwi E. N. 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