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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31549/2542-1174-2025-9-3-160-169</article-id><article-id custom-type="elpub" pub-id-type="custom">jsms-1235</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РЕЗОЛЮЦИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>RESOLUTION</subject></subj-group></article-categories><title-group><article-title>Резолюция Экспертного совета по разработке региональной программы по ранней диагностике сахарного диабета 1 типа у детского населения и проведению профилактических мероприятий среди пациентов из групп риска</article-title><trans-title-group xml:lang="en"><trans-title>Resolution of the Expert Board on the development of a regional program for the early diagnosis of type 1 diabetes in children and the implementation of preventive measures among patients at risk</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6762-5238</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руяткина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ruyatkina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Руяткина Людмила Александровна – д-р мед. наук, профессор, профессор кафедры неотложной терапии с эндокринологией и профпатологией; председатель Ассоциации эндокринологов Новосибирской области</p><p>630091, г. Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Lyudmila A. Ruyatkina – Dr. Sci. (Med.), Professor, Professor of Department of Emergency Medicine with Endocrino logy and Occupational Pathology; Chairman, Association of Endocrinologists of the Novosibirsk region</p><p>52, Krasny prosp., Novosibirsk, 630091</p></bio><email xlink:type="simple">larut@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2500-8001</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Таранушенко</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Taranushenko</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Таранушенко Татьяна Евгеньевна – д-р мед. наук, профессор, заведующий кафедрой педиатрии Института последипломного образования; главный внештатный специалист – детский эндокринолог Минздрава России в Сибирском федеральном округе; главный внештатный специалист – детский эндокринолог Минздрава Красноярского края</p><p>Красноярск</p></bio><bio xml:lang="en"><p>Tatiana E. Taranushenko – Dr. Sci. (Med.), Professor, Head, Department of Pediatrics, Institute of Pоstdiploma Education; Chief Pediatric Endocrinology Consultant, Ministry of Health of the Russian Federation in the Siberian Federal District; Chief Pediatric Endocrinology Consultant, Ministry of Health of the Krasnoyarsk region</p><p>Krasnoyarsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2667-4842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самойлова</surname><given-names>Ю. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Samoylova</surname><given-names>Yu. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самойлова Юлия Геннадьевна – д-р мед. наук, профессор, детский эндокринолог, директор; руководитель Центра клинических исследований Сибирского федерального округа</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Yulia G. Samoylova – Dr. Sci. (Med.), Professor, Pediatric Endocrinologist, Director; Head, Center of Clinical Investigaions of the Siberian Federal District</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7958-0081</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пилипенко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pilipenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пилипенко Оксана Владимировна – руководитель Городского детского центра обменных и эндокринных нарушений</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Oksana V. Pilipenko – Head</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5012-0364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваренко</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovarenko</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коваренко Маргарита Анатольевна – канд. мед. наук, доцент кафедры педиатрии (факультет повышения квалификации и профессиональной подготовки врачей)</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Margarita A. Kovarenko – Cand. Sci. (Med.), Associate Professor, Department of Pediatrics (Faculty of Advanced Training and Professional Training of Doctors</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тайлакова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tailakova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тайлакова Евгения Анатольевна – главный внештатный специалист – детский эндокринолог Минздрава Алтайского края; врач – детский эндокринолог</p><p>Барнаул</p></bio><bio xml:lang="en"><p>Evgenia A. Tailakova – Chief Pediatric Endocrinology Consultant, Ministry of Health of the Altai Territory; Pediatric Endocrinologist</p><p>Barnaul </p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Санникова</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sannikova</surname><given-names>L. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санникова Лариса Владимировна – главный внештатный специалист – детский эндокринолог Минздрава Новосибирской области; врач – детский эндокринолог</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Larisa V. Sannikova – Chief Pediatric Endocrino logy Consultant, Ministry of Health of the Novosibirsk region; Pediatric Endocrinologist</p><p>Novosibirsk </p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5669-1718</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Власенко</surname><given-names>Н. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Vlasenko</surname><given-names>N. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Власенко Наталья Юрьевна – канд. мед. наук, доцент кафедры госпитальной педиатрии с курсом дополнительного профессионального образования; главный внештатный специалист – детский эндокринолог Минздрава Омской области</p><p>Омск</p></bio><bio xml:lang="en"><p>Natalia Yu. Vlasenko – Cand. Sci. (Med.), Associate Professor, Departments of Hospital Pediatrics with a Course of Additional Professional Education; Chief Pediatric Endocrinology Consultant, Ministry of Health of the Omsk region</p><p>Omsk</p></bio><xref ref-type="aff" rid="aff-7"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский государственный медицинский университет им. проф. В.Ф. Войно-Ясенецкого» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт медицины и медицинских технологий Новосибирского государственного университета</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of Medicine and Medical Technologies, Novosibirsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Городской детский центр обменных и эндокринных нарушений ГБУЗ НСО «Детская городская клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Children’s Center for Metabolic and Endocrine Disorders, Children’s City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>КГБУЗ «Алтайский краевой клинический центр охраны материнства и детства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Altai Regional Clinical Center for Maternal and Child Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>ГБУЗ НСО «Государственная Новосибирская областная клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>ФГБОУ ВО «Омский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Omsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>02</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>160</fpage><lpage>169</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Руяткина Л.А., Таранушенко Т.Е., Самойлова Ю.Г., Пилипенко О.В., Коваренко М.А., Тайлакова Е.А., Санникова Л.В., Власенко Н.Ю., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Руяткина Л.А., Таранушенко Т.Е., Самойлова Ю.Г., Пилипенко О.В., Коваренко М.А., Тайлакова Е.А., Санникова Л.В., Власенко Н.Ю.</copyright-holder><copyright-holder xml:lang="en">Ruyatkina L.A., Taranushenko T.E., Samoylova Y.G., Pilipenko O.V., Kovarenko M.A., Tailakova E.A., Sannikova L.V., Vlasenko N.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/1235">https://jsms.elpub.ru/jour/article/view/1235</self-uri><abstract><p>Распространенность сахарного диабета 1 типа (СД1) продолжает расти, и, несмотря на достижения в инсулинотерапии, добиться оптимального контроля СД1 не удается. Его клинический дебют часто ассоциирован с диабетическим кетоацидозом, который программирует высокий риск повторных эпизодов и раннего развития тяжелых осложнений, определяя бремя, создаваемое болезнью, и актуализируя разработку комплекса целевых мероприятий по раннему выявлению доклинических стадий заболевания.</p><p>20 марта 2025 г. в г. Новосибирске состоялась научно-практическая конференция «Детская и подростковая эндокринология: возможности, трудности, ошибки», в рамках которой состоялся Экспертный совет детских эндокринологов Сибирского федерального округа. Основное внимание на конференции было уделено достижениям науки в области изучения СД1 и внедрению стратегии его раннего выявления и мониторинга в практику эндокринолога. По результатам проведенных в ходе Экспертного совета научных докладов и дискуссии эксперты приняли решение о необходимости внедрения социально значимой инициативы по своевременной диагностике СД1 до его клинической манифестации с целью профилактики дебюта заболевания кетоацидозом, значимо ухудшающим прогноз дальнейшего течения заболевания, и снижению риска развития осложнений.</p></abstract><trans-abstract xml:lang="en"><p>The prevalence of type 1 diabetes mellitus (T1DM) continues to grow, and despite the advances in insulin therapy, the optimal control of T1DM is not achieved yet. Its clinical onset is often associated with diabetic ketoacidosis, which determines a high risk of recurrent events and early development of severe complications, determining the disease burden and necessitating the development of a set of specific arrangements for early detection of preclinical stages of the disease.</p><p>On March 20, 2025, a scientific and practical conference “Pediatric and Adolescent Endocrinology: Opportunities, Challenges, and Mistakes” was held in Novosibirsk, which included an Expert Board of pediatric endocrinologists from the Siberian Federal District. The conference focused on scientific advances in the study of T1DM and implementing strategies for its early detection and monitoring in real-life endocrinologic practice. Based on the results of scientific reports and discussions held during the Expert Board meeting, experts decided on the need to implement a socially significant initiative for the timely diagnosis of T1DM before its clinical manifestation in order to prevent its onset with ketoacidosis, which significantly worsens the disease prognosis, and to reduce the risk of complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сахарный диабет 1 типа</kwd><kwd>доклиническая диагностика</kwd><kwd>антитела</kwd></kwd-group><kwd-group xml:lang="en"><kwd>type 1 diabetes mellitus</kwd><kwd>preclinical diagnostics</kwd><kwd>antibodies</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Перечень поручений Президента Российской Федерации по итогам встречи с членами Общероссийской общественной организации «Деловая Россия» (утв. Президентом РФ 26.04.2022 N Пр-740). URL: https://www.consultant.ru/document/cons_doc_LAW_415917/ (дата обращения 20.06.2025).</mixed-citation><mixed-citation xml:lang="en">List of instructions from the President of the Russian Federation following a meeting with members of the All-Russian Public Organization “Business Russia” (approved by the President of the Russian Federation 26.04.2022 No. Pr-740). URL: https://www.consultant.ru/document/cons_doc_LAW_415917/ (accessed 20.06.2025).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Федеральный проект «Борьба с сахарным диабетом». URL: https://diabet.endocrincentr.ru/specialistam/federalnye_proekty (дата обращения 20.06.2025).</mixed-citation><mixed-citation xml:lang="en">Federal Project “Diabetes mellitus Control” URL: https://diabet.endocrincentr.ru/specialistam/federalnye_proekty (accessed 20.06.2025).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Сахарный диабет 1 типа у детей: клинические рекомендации. 2025. https://cr.minzdrav.gov.ru/preview-cr/287_3 (дата обращения 20.06.2025).</mixed-citation><mixed-citation xml:lang="en">Type 1 diabetes mellitus in children: clinical guidelines. 2025. https://cr.minzdrav.gov.ru/preview-cr/287_3 (accessed 20.06.2025).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">О федеральном бюджете на 2025 год и на плановый период 2026 и 2027 годов: федеральный закон от 30.11.2024 N 419-ФЗ. URL: http://government.ru/docs/all/156651/ (дата обращения 20.06.2025).</mixed-citation><mixed-citation xml:lang="en">On the Federal Budget for 2025 and for the planning period of 2026 and 2027: Federal Law No. 419- FZ of 11.30.2024. URL: http://government.ru/docs/all/156651/ (accessed 20.06.2025).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ziegler A.G., Rewers M., Simell O. et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children // JAMA. 2013 19;309(23):2473- 2479. DOI: 10.1001/jama.2013.6285.</mixed-citation><mixed-citation xml:lang="en">Ziegler A.G., Rewers M., Simell O. et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA. 2013 19;309(23):2473- 2479. DOI: 10.1001/jama.2013.6285.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Parikka V., Näntö-Salonen K., Saarinen M. et al. Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk // Diabetologia. 2012;55(7):1926-1936. DOI: 10.1007/s00125-012-2523-3.</mixed-citation><mixed-citation xml:lang="en">Parikka V., Näntö-Salonen K., Saarinen M. et al. Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk // Diabetologia. 2012;55(7):1926-1936. DOI: 10.1007/s00125-012-2523-3.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Insel R.A., Dunne J.L., Atkinson M.A. et al. Staging presymptomatic type 1 diabetes: a scientifi c statement of JDRF, the Endocrine Society, and the American Diabetes Association // Diabetes Care. 2015;38(10):1964- 1974. DOI: 10.2337/dc15-1419.</mixed-citation><mixed-citation xml:lang="en">Insel R.A., Dunne J.L., Atkinson M.A. et al. Staging presymptomatic type 1 diabetes: a scientifi c statement of JDRF, the Endocrine Society, and the American Diabetes Association. Diabetes Care. 2015;38(10):1964- 1974. DOI: 10.2337/dc15-1419.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Barker J.M., Goehrig S.H., Barriga K. et al. Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up// Diabetes Care. 2004;27(6):1399-1404. DOI: 10.2337/diacare.27.6.1399.</mixed-citation><mixed-citation xml:lang="en">Barker J.M., Goehrig S.H., Barriga K. et al. Clinical characteristics of children diagnosed with type 1 diabetes through intensive screening and follow-up. Diabetes Care. 2004;27(6):1399-1404. DOI: 10.2337/diacare.27.6.1399.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ehrmann D., Kulzer B., Roos T. et al. Risk factors and prevention strategies for diabetic ketoacidosis in people with established type 1 diabetes // Lancet Diabetes Endocrinol. 2020;8(5):436-446. DOI: 10.1016/S2213-8587(20)30042-5.</mixed-citation><mixed-citation xml:lang="en">Ehrmann D., Kulzer B., Roos T. et al. Risk factors and prevention strategies for diabetic ketoacidosis in people with established type 1 diabetes. Lancet Diabetes Endocrinol. 2020;8(5):436-446. DOI: 10.1016/S2213-8587(20)30042-5.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Primavera M., Giannini C., Chiarelli F. Prediction and prevention of type 1 diabetes // Front. Endocrinol. (Lausanne). 2020;11:248. DOI: 10.3389/fendo.2020.00248.</mixed-citation><mixed-citation xml:lang="en">Primavera M., Giannini C., Chiarelli F. Prediction and prevention of type 1 diabetes. Front. Endocrinol. (Lausanne). 2020;11:248. DOI: 10.3389/fendo.2020.00248.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Peters A. Screening for autoantibodies in type 1 diabetes: A call to action // J. Fam. Pract. 2021;70(6S):S47- S52. DOI: 10.12788/jfp.0223.</mixed-citation><mixed-citation xml:lang="en">Peters A. Screening for autoantibodies in type 1 diabetes: A call to action // J. Fam. Pract. 2021;70(6S):S47- S52. DOI: 10.12788/jfp.0223.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">So M., Speake C., Steck A.K. et al. Advances in type 1 diabetes prediction using islet autoantibodies: Beyond a simple count // Endocr. Rev. 2021;42(5):584-604. DOI: 10.1210/endrev/bnab013.</mixed-citation><mixed-citation xml:lang="en">So M., Speake C., Steck A.K. et al. Advances in type 1 diabetes prediction using islet autoantibodies: Beyond a simple count. Endocr. Rev. 2021;42(5):584-604. DOI: 10.1210/endrev/bnab013.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Ziegler A.G., Kick K., Bonifacio E. et al.; Fr1da Study Group. Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany // JAMA. 2020;323(4):339-351. DOI: 10.1001/jama.2019.21565.</mixed-citation><mixed-citation xml:lang="en">Ziegler A.G., Kick K., Bonifacio E. et al.; Fr1da Study Group. Yield of a public health screening of children for islet autoantibodies in Bavaria, Germany. JAMA. 2020;323(4):339-351. DOI: 10.1001/jama.2019.21565.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Pöllänen P.M., Ryhänen S.J., Toppari J. et al. Dynamics of islet autoantibodies during prospective follow-up from birth to age 15 years // J. Clin. Endocrinol. Metab. 2020;105(12):e4638-e4651. DOI: 10.1210/clinem/dgaa624.</mixed-citation><mixed-citation xml:lang="en">Pöllänen P.M., Ryhänen S.J., Toppari J. et al. Dynamics of islet autoantibodies during prospective follow-up from birth to age 15 years. J. Clin. Endocrinol. Metab. 2020;105(12):e4638-e4651. DOI: 10.1210/clinem/dgaa624.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Sims E.K., Besser R.E.J., Dayan C. et al.; NIDDK Type 1 Diabetes TrialNet Study Group. Screening for type 1 diabetes in the general population: A status report and perspective // Diabetes. 2022;71(4):610-623. DOI: 10.2337/dbi20-0054.</mixed-citation><mixed-citation xml:lang="en">Sims E.K., Besser R.E.J., Dayan C. et al.; NIDDK Type 1 Diabetes TrialNet Study Group. Screening for type 1 diabetes in the general population: A status report and perspective. Diabetes. 2022;71(4):610-623. DOI: 10.2337/dbi20-0054.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Ранняя диагностика и лечение сахарного диабета 1 типа. Вопросы клинической целесообразности, организации и доступности медицинской помощи // Медицинские технологии. Оценка и выбор. 2025;47(2):10-17. DOI: 10.17116/medtech20254702110.</mixed-citation><mixed-citation xml:lang="en">Early diagnosis and treatment of type 1 diabetes mellitus. Issues of clinical feasibility, organization, and accessibility of medical care. Resolution on the results of the Expert Council held on December 17, 2024, Moscow. Medical Technologies. Assessment and Choice. 2025;47(2):10-17. DOI: 10.17116/ medtech20254702110. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Gomez-Lopera N., Pineda-Trujillo N., Diaz-Valencia P.A. Correlating the global increase in type 1 diabetes incidence across age groups with national economic prosperity: A systematic review // World J. Diabetes. 2019;10(12):560-580. DOI: 10.4239/wjd.v10.i12.560.</mixed-citation><mixed-citation xml:lang="en">Gomez-Lopera N., Pineda-Trujillo N., Diaz-Valencia P.A. Correlating the global increase in type 1 diabetes incidence across age groups with national economic prosperity: A systematic review. World J. Diabetes. 2019;10(12):560-580. DOI: 10.4239/wjd.v10.i12.560.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Лаптев Д.Н., Безлепкина О.В., Шешко Е.Л. и др. Основные эпидемиологические показатели сахарного диабета 1 типа у детей в Российской Федерации за 2014–2023 год // Проблемы эндокринологии. 2024;70(5):76-83. DOI: 10.14341/probl13515.</mixed-citation><mixed-citation xml:lang="en">Laptev D.N., Bezlepkina O.B., Sheshko E.L. et al. Main epidemiological indicators of type 1 diabetes mellitus in children in the Russian Federation for 2014–2023. Problems of Endocrinology. 2024;70(5):76-83. DOI: 10.14341/probl13515. (In Russ.)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Phillip M., Achenbach P., Addala A. et al. Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes // Diabetologia. 2024;67(9):1731-1759. DOI: 10.1007/s00125-024-06205-5.</mixed-citation><mixed-citation xml:lang="en">Phillip M., Achenbach P., Addala A. et al. Consensus guidance for monitoring individuals with islet autoantibody-positive pre-stage 3 type 1 diabetes. Diabetologia. 2024;67(9):1731-1759. DOI: 10.1007/s00125-024-06205-5.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
