<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-283</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.01.00 КЛИНИЧЕСКАЯ МЕДИЦИНА)</subject></subj-group></article-categories><title-group><article-title>ОБЗОР СОВРЕМЕННЫХ ТЕНДЕНЦИЙ ДИАГНОСТИКИ, КОНСЕРВАТИВНОГО И ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ АХАЛАЗИИ КАРДИИ</article-title><trans-title-group xml:lang="en"><trans-title>REVIEW OF MODERN TRENDS OF DIAGNOSTICS, CONSERVATIVE AND SURGICALTREATMENTS AT ACHALASIA OF CARDIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анищенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Anishchenko</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">AVV1110@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ковган</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovgan</surname><given-names>Y. M.</given-names></name></name-alternatives><email xlink:type="simple">kovgan_julius@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Платонов</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Platonov</surname><given-names>P. A.</given-names></name></name-alternatives><email xlink:type="simple">pplatonoff@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО «Новосибирский государственный медицинский университет» Минздрава России; НУЗ «Дорожная клиническая больница на ст. Новосибирск-Главный ОАО „РЖД“»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SBEI HPE «Novosibirsk State Medical University of Ministry of Health»; NHE «Road clinic hospital PLC The Russian Railways (RZhD)»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>5</issue><fpage>33</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Анищенко В.В., Ковган Ю.М., Платонов П.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Анищенко В.В., Ковган Ю.М., Платонов П.А.</copyright-holder><copyright-holder xml:lang="en">Anishchenko V.V., Kovgan Y.M., Platonov P.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/283">https://jsms.elpub.ru/jour/article/view/283</self-uri><abstract><p>Цель исследования. В связи с определившейся в последнее время направленностью отечественной медицины на создание четко оговоренных алгоритмов и рекомендаций по лечению большинства основных нозологических форм имеет смысл произвести обзор наиболее актуальной на сегодняшний день информации по современным тенденциям диагностики и лечения ахалазии кардии. Проведен обзор иностранных статей и рекомендаций.</p></abstract><trans-abstract xml:lang="en"><p>Research objective . Due to the orientation of domestic medicine that was recently defined on creation of accurately stipulated algorithms and references on treatment of the majority of the main nosological forms it is added up to create the review of most actual and modern information on current trends of diagnostics and treatment of achalasia of cardia. The review of foreign articles and references performed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ахалазия кардии</kwd><kwd>миотомия</kwd><kwd>баллонная дилатация</kwd><kwd>ботулотоксин</kwd><kwd>дисфагия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>cardia achalasia</kwd><kwd>myotomy</kwd><kwd>balloon dilatation</kwd><kwd>botulotoxin</kwd><kwd>dysphagia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Endoscopic and surgical treatments for achalasia : a systematic review and meta-analysis / G. M. Campos [et al.] // Ann. Surg. - 2009. - Vol. 249. - Р. 45-57.</mixed-citation><mixed-citation xml:lang="en">Endoscopic and surgical treatments for achalasia : a systematic review and meta-analysis / G. M. Campos [et al.] // Ann. Surg. - 2009. - Vol. 249. - Р. 45-57.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Goldblum J. R. Histopathologic features in esophagomyotomy specimens from patients with achalasia / J. R. Goldblum, T. W. Rice, J. E. Richter // Gastroenterology. - 1996. - Vol. 111. - Р. 648-654.</mixed-citation><mixed-citation xml:lang="en">Goldblum J. R. Histopathologic features in esophagomyotomy specimens from patients with achalasia / J. R. Goldblum, T. W. Rice, J. E. Richter // Gastroenterology. - 1996. - Vol. 111. - Р. 648-654.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Woltman T. A. Achalasia / T. A. Woltman, C. A. Pellegrini, B. K. Oelschlager // Surg. Clin. North. Am. - 2005. - Vol. 85. - Р. 483-493.</mixed-citation><mixed-citation xml:lang="en">Woltman T. A. Achalasia / T. A. Woltman, C. A. Pellegrini, B. K. Oelschlager // Surg. Clin. North. Am. - 2005. - Vol. 85. - Р. 483-493.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Vaezi M. F. Diagnosis and management of achalasia. American College of Gastroenterology Practice Parameter Committee / M. F. Vaezi, J. E. Richter // Am. J. Gastroenterol. - 1999. - Vol. 94. - Р. 3406-3412.</mixed-citation><mixed-citation xml:lang="en">Vaezi M. F. Diagnosis and management of achalasia. American College of Gastroenterology Practice Parameter Committee / M. F. Vaezi, J. E. Richter // Am. J. Gastroenterol. - 1999. - Vol. 94. - Р. 3406-3412.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Eckardt A. J. Current clinical approach to achalasia / A. J. Eckardt, V. F. Eckardt // World J. Gastroenterol. - 2009. - Vol. 15. - Р. 3969-3975.</mixed-citation><mixed-citation xml:lang="en">Eckardt A. J. Current clinical approach to achalasia / A. J. Eckardt, V. F. Eckardt // World J. Gastroenterol. - 2009. - Vol. 15. - Р. 3969-3975.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Wen Z. H. Nitrates for achalasia / Z. H. Wen, E. Gardener, Y. P. Wang // Cochrane Database Syst. Rev. - 2004. - Vol. 1. - CD002299.</mixed-citation><mixed-citation xml:lang="en">Wen Z. H. Nitrates for achalasia / Z. H. Wen, E. Gardener, Y. P. Wang // Cochrane Database Syst. Rev. - 2004. - Vol. 1. - CD002299.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bassotti G. Review article: pharmacological options in achalasia / G. Bassotti, V. Annese // Aliment. Pharmacol. Ther. - 1999. - Vol. 13. - Р. 1391-1396.</mixed-citation><mixed-citation xml:lang="en">Bassotti G. Review article: pharmacological options in achalasia / G. Bassotti, V. Annese // Aliment. Pharmacol. Ther. - 1999. - Vol. 13. - Р. 1391-1396.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Annese V. Non-surgical treatment of esophageal achalasia / V. Annese, G. Bassotti // World J. Gastroenterol. - 2006. - Vol. 12. - Р. 5763-5766.</mixed-citation><mixed-citation xml:lang="en">Annese V. Non-surgical treatment of esophageal achalasia / V. Annese, G. Bassotti // World J. Gastroenterol. - 2006. - Vol. 12. - Р. 5763-5766.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Treatment of achalasia : the short-term response to botulinum toxin injection seems to be independent of any kind of pretreatment / М. Storr [et al.] // BMC Gastroenterol. - 2002. - Vol. 2. - Р. 19.</mixed-citation><mixed-citation xml:lang="en">Treatment of achalasia : the short-term response to botulinum toxin injection seems to be independent of any kind of pretreatment / М. Storr [et al.] // BMC Gastroenterol. - 2002. - Vol. 2. - Р. 19.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Treatment of patients with achalasia with botulinum toxin : a multicenter prospective cohort study / J. Martinek [et al.] // Dis. Esophagus. - 2003. - Vol. 16. - Р. 204-209.</mixed-citation><mixed-citation xml:lang="en">Treatment of patients with achalasia with botulinum toxin : a multicenter prospective cohort study / J. Martinek [et al.] // Dis. Esophagus. - 2003. - Vol. 16. - Р. 204-209.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Botulinum toxin for achalasia : long-term outcome and predictors of response / P. J. Pasricha [et al.] // Gastroenterology. - 1996. - Vol. 110. - Р. 1410-1415.</mixed-citation><mixed-citation xml:lang="en">Botulinum toxin for achalasia : long-term outcome and predictors of response / P. J. Pasricha [et al.] // Gastroenterology. - 1996. - Vol. 110. - Р. 1410-1415.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Treatment of achalasia : botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-Up / H. D. Allescher [et al.] // Endoscopy. - 2001. - Vol. 33. - Р. 1007-1017.</mixed-citation><mixed-citation xml:lang="en">Treatment of achalasia : botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-Up / H. D. Allescher [et al.] // Endoscopy. - 2001. - Vol. 33. - Р. 1007-1017.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">A multicentre randomised study of intrasphincteric botulinum toxin in patients with oesophageal achalasia / V. Annese [et al.] // GISMAD Achalasia Study Group. Gut. - 2000. - Vol. 46. - Р. 597-600.</mixed-citation><mixed-citation xml:lang="en">A multicentre randomised study of intrasphincteric botulinum toxin in patients with oesophageal achalasia / V. Annese [et al.] // GISMAD Achalasia Study Group. Gut. - 2000. - Vol. 46. - Р. 597-600.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Treatment with botulinum toxin of octo-nonagerians with oesophageal achalasia : a two-year follow-up study / G. Bassotti [et al.] // Aliment. Pharmacol. Ther. - 2006. - Vol. 23. - Р. 1615-1619.</mixed-citation><mixed-citation xml:lang="en">Treatment with botulinum toxin of octo-nonagerians with oesophageal achalasia : a two-year follow-up study / G. Bassotti [et al.] // Aliment. Pharmacol. Ther. - 2006. - Vol. 23. - Р. 1615-1619.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Manometric evaluation of achalasia in the elderly / N. Hashemi [et al.] // Aliment. Pharmacol. Ther. - 2005. - Vol. 21. - Р. 431-434.</mixed-citation><mixed-citation xml:lang="en">Manometric evaluation of achalasia in the elderly / N. Hashemi [et al.] // Aliment. Pharmacol. Ther. - 2005. - Vol. 21. - Р. 431-434.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Long-term results and prognostic factors in the treatment of achalasia with botulinum toxin / М. Neubrand [et al.] // Endoscopy. - 2002. - Vol. 34. - Р. 519-523.</mixed-citation><mixed-citation xml:lang="en">Long-term results and prognostic factors in the treatment of achalasia with botulinum toxin / М. Neubrand [et al.] // Endoscopy. - 2002. - Vol. 34. - Р. 519-523.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Long-term efficacy of Botulinum toxin in classical achalasia : a prospective study / J. Kolbasnik [et al.] // Am. J. Gastroenterol. - 1999. - Vol. 94. - Р. 3434-3439.</mixed-citation><mixed-citation xml:lang="en">Long-term efficacy of Botulinum toxin in classical achalasia : a prospective study / J. Kolbasnik [et al.] // Am. J. Gastroenterol. - 1999. - Vol. 94. - Р. 3434-3439.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Mac Iver R. A case of mediastinitis following botulinum toxin type A treatment for achalasia / R. Mac Iver, M. Liptay, Y. Johnson // Nat. Clin. Pract. Gastroenterol. Hepatol. - 2007. - Vol. 4. - Р. 579-582.</mixed-citation><mixed-citation xml:lang="en">Mac Iver R. A case of mediastinitis following botulinum toxin type A treatment for achalasia / R. Mac Iver, M. Liptay, Y. Johnson // Nat. Clin. Pract. Gastroenterol. Hepatol. - 2007. - Vol. 4. - Р. 579-582.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Fatal heart block following treatment with botulinum toxin for achalasia / S. D. Malnick [et al.] // Am. J. Gastroenterol. - 2000. - Vol. 95. - Р. 3333-3334.</mixed-citation><mixed-citation xml:lang="en">Fatal heart block following treatment with botulinum toxin for achalasia / S. D. Malnick [et al.] // Am. J. Gastroenterol. - 2000. - Vol. 95. - Р. 3333-3334.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Leyden J. E. Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia / J. E. Leyden, A. C. Moss, P. MacMathuna // Cochrane Database Syst. Rev. - 2006. - CD005046.</mixed-citation><mixed-citation xml:lang="en">Leyden J. E. Endoscopic pneumatic dilation versus botulinum toxin injection in the management of primary achalasia / J. E. Leyden, A. C. Moss, P. MacMathuna // Cochrane Database Syst. Rev. - 2006. - CD005046.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">A systematic review and meta-analysis of the Chinese literature for the treatment of achalasia / L. Wang [et al.] // World J. Gastroenterol. - 2008. - Vol. 14. - Р. 5900-5906.</mixed-citation><mixed-citation xml:lang="en">A systematic review and meta-analysis of the Chinese literature for the treatment of achalasia / L. Wang [et al.] // World J. Gastroenterol. - 2008. - Vol. 14. - Р. 5900-5906.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Comparison of two different formulations of botulinum toxin A for the treatment of oesophageal achalasia. The Gismad Achalasia Study Group / V. Annese [et al.] // Aliment. Pharmacol. Ther. - 1999. - Vol. 13. - Р. 1347-1350.</mixed-citation><mixed-citation xml:lang="en">Comparison of two different formulations of botulinum toxin A for the treatment of oesophageal achalasia. The Gismad Achalasia Study Group / V. Annese [et al.] // Aliment. Pharmacol. Ther. - 1999. - Vol. 13. - Р. 1347-1350.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Pohl D. Achalasia : an overview of diagnosis and treatment / D. Pohl, R. Tutuian // J. Gastrointestin Liver. Dis. - 2007. - Vol. 16. - Р. 297-303.</mixed-citation><mixed-citation xml:lang="en">Pohl D. Achalasia : an overview of diagnosis and treatment / D. Pohl, R. Tutuian // J. Gastrointestin Liver. Dis. - 2007. - Vol. 16. - Р. 297-303.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Kadakia S. C. Pneumatic balloon dilation for esophageal achalasia / S. C. Kadakia, R. K. Wong // Gastrointest. Endosc. Clin. N. Am. - 2001. - Vol. 11. - Р. 325-346.</mixed-citation><mixed-citation xml:lang="en">Kadakia S. C. Pneumatic balloon dilation for esophageal achalasia / S. C. Kadakia, R. K. Wong // Gastrointest. Endosc. Clin. N. Am. - 2001. - Vol. 11. - Р. 325-346.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Endoscope-guided pneumatic dilatation of esophageal achalasia without fluoroscopy is another safe and effective treatment option : a report of Taiwan / S. K. Chuah [et al.] // Surg. Laparosc. Endosc. Percutan. Tech. - 2008. - Vol. 18. - Р. 8-12.</mixed-citation><mixed-citation xml:lang="en">Endoscope-guided pneumatic dilatation of esophageal achalasia without fluoroscopy is another safe and effective treatment option : a report of Taiwan / S. K. Chuah [et al.] // Surg. Laparosc. Endosc. Percutan. Tech. - 2008. - Vol. 18. - Р. 8-12.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Eckardt V. F. Pneumatic dilation for achalasia : late results of a prospective follow up investigation / V. F. Eckardt, I. Gockel, G. Bernhard // Gut. - 2004. - Vol. 53. - Р. 629-633.</mixed-citation><mixed-citation xml:lang="en">Eckardt V. F. Pneumatic dilation for achalasia : late results of a prospective follow up investigation / V. F. Eckardt, I. Gockel, G. Bernhard // Gut. - 2004. - Vol. 53. - Р. 629-633.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Long-term results of pneumatic dilation for achalasia : a 15 years’ experience / P. Katsinelos [et al.] // World J. Gastroenterol. - 2005. - Vol. 11. - Р. 5701-5705.</mixed-citation><mixed-citation xml:lang="en">Long-term results of pneumatic dilation for achalasia : a 15 years’ experience / P. Katsinelos [et al.] // World J. Gastroenterol. - 2005. - Vol. 11. - Р. 5701-5705.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Long term results of pneumatic dilation in achalasia followed for more than 5 years / R. L. West [et al.] // Am. J. Gastroenterol. - 2002. - Vol. 97. - Р. 1346-1351.</mixed-citation><mixed-citation xml:lang="en">Long term results of pneumatic dilation in achalasia followed for more than 5 years / R. L. West [et al.] // Am. J. Gastroenterol. - 2002. - Vol. 97. - Р. 1346-1351.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Repeated pneumatic dilations as long-term maintenance therapy for esophageal achalasia / F. Zerbib [et al.] // Am. J. Gastroenterol. - 2006. - Vol. 101. - Р. 692-697.</mixed-citation><mixed-citation xml:lang="en">Repeated pneumatic dilations as long-term maintenance therapy for esophageal achalasia / F. Zerbib [et al.] // Am. J. Gastroenterol. - 2006. - Vol. 101. - Р. 692-697.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Heller myotomy for failed pneumatic dilation in achalasia : how effective is it? / I. Gockel [et al.] // Ann. Surg. - 2004. - Vol. 239. - Р. 371-377.</mixed-citation><mixed-citation xml:lang="en">Heller myotomy for failed pneumatic dilation in achalasia : how effective is it? / I. Gockel [et al.] // Ann. Surg. - 2004. - Vol. 239. - Р. 371-377.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
