<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-325</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.01.00 КЛИНИЧЕСКАЯ МЕДИЦИНА)</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ МЕТАБОЛИЧЕСКОГО СИНДРОМА НА ПАРАМЕТРЫ ЭЯКУЛЯТА У БОЛЬНЫХ ТУБЕРКУЛЕЗОМ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>INFLUENCE OF METABOLIC SYNDROME ON EJACULATE PARAMETERS AT PATIENTS WITH PROSTATIC TUBERCULOSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кульчавеня</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kulchavenya</surname><given-names>E. V.</given-names></name></name-alternatives><email xlink:type="simple">urotub@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Осадчий</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Osadchy</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">urotub@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Новосибирский НИИ туберкулёза» Минздрава России; ГБОУ ВПО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FBHE «Novosibirsk SRI of tuberculosis» of Ministry of Health; SBEI HPE «Novosibirsk State Medical University of Ministry of Health»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБУ «Новосибирский НИИ туберкулёза» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FBHE «Novosibirsk SRI of tuberculosis» of Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>6</issue><fpage>19</fpage><lpage>19</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кульчавеня Е.В., Осадчий А.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Кульчавеня Е.В., Осадчий А.В.</copyright-holder><copyright-holder xml:lang="en">Kulchavenya E.V., Osadchy A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/325">https://jsms.elpub.ru/jour/article/view/325</self-uri><abstract><p>С целью определения основных показателей метаболического и гормонального статуса и уровня нарушения сперматогенеза у больных туберкулезом предстательной железы проведено исследование, в которое включили 72 пациента с туберкулезом предстательной железы, госпитализированных в отделение урогенитального туберкулеза ФГБУ «ННИИТ» Минздрава России в период с 2012 по 2014 год. Установлено, что у 41 % больных туберкулезом простаты имеется метаболический синдром, который усугубляет негативное влияние основного заболевания на показатели эякулята.</p></abstract><trans-abstract xml:lang="en"><p>The research in which 72 patients with prostatic tuberculosis hospitalized in unit of urogenital tuberculosis at FSBE «NSRIT» of the Russian Ministry of Health during the period starting on 2012 and continuing through inclusive 2014 is conducted for the purpose of defining the main indicators of the metabolic and hormonal status and level of disturbance of spermatogenesis at patients with prostatic tuberculosis. It is established that 41% of patients with prostatic tuberculosis have metabolic syndrome which aggravates negative influence of a basic disease on ejaculate indicators.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>туберкулез</kwd><kwd>простата</kwd><kwd>предстательная железа</kwd><kwd>метаболический синдром</kwd><kwd>бесплодие</kwd><kwd>сперматозоид</kwd><kwd>эякулят</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tuberculosis</kwd><kwd>prostate</kwd><kwd>metabolic syndrome</kwd><kwd>sterility</kwd><kwd>spermatozoon</kwd><kwd>ejaculate</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">The metabolic syndrome / R. H. Eckel [et al.] // Lancet. - 2010. - Vol. 375. - Р. 181-3.</mixed-citation><mixed-citation xml:lang="en">The metabolic syndrome / R. H. Eckel [et al.] // Lancet. - 2010. - Vol. 375. - Р. 181-3.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Testosterone, cardiovascular disease and the metabolic syndrome / G. Corona [et al.] // Best Pract. Res. Clin. Endocrinol. Metab. - 2011. - Vol. 25. - Р. 337-53.</mixed-citation><mixed-citation xml:lang="en">Testosterone, cardiovascular disease and the metabolic syndrome / G. Corona [et al.] // Best Pract. Res. Clin. Endocrinol. Metab. - 2011. - Vol. 25. - Р. 337-53.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Hypogonadism and metabolic syndrome / G. Corona [et al.] // J. Endocrinol. Invest. - 2011. - Vol. 34. - Р. 557-67.</mixed-citation><mixed-citation xml:lang="en">Hypogonadism and metabolic syndrome / G. Corona [et al.] // J. Endocrinol. Invest. - 2011. - Vol. 34. - Р. 557-67.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of The National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) // JAMA. - 2001. - Vol. 285. - Р. 2486-97.</mixed-citation><mixed-citation xml:lang="en">Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of The National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) // JAMA. - 2001. - Vol. 285. - Р. 2486-97.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Metabolic syndrome and prostate abnormalities in male subjects of infertile couples / F. Lotti [et al.] // Asian J. Androl. - 2014 Mar-Apr. - Vol. 16 (2). - Р. 295-304.</mixed-citation><mixed-citation xml:lang="en">Metabolic syndrome and prostate abnormalities in male subjects of infertile couples / F. Lotti [et al.] // Asian J. Androl. - 2014 Mar-Apr. - Vol. 16 (2). - Р. 295-304.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chronic inflammation in the pathogenesis of benign prostatic hyperplasia / В. Fibbi [et al.] // Int. J. Andr. - 2009. - Vol. 32. - Р. 1-15.</mixed-citation><mixed-citation xml:lang="en">Chronic inflammation in the pathogenesis of benign prostatic hyperplasia / В. Fibbi [et al.] // Int. J. Andr. - 2009. - Vol. 32. - Р. 1-15.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ultrasonographic and clinical correlates of seminal plasma interleukin-8 levels in patients attending an andrology clinic for infertility / F. Lotti [et al.] // Int. J. Androl. - 2011. - Vol. 34. - Р. 600-13.</mixed-citation><mixed-citation xml:lang="en">Ultrasonographic and clinical correlates of seminal plasma interleukin-8 levels in patients attending an andrology clinic for infertility / F. Lotti [et al.] // Int. J. Androl. - 2011. - Vol. 34. - Р. 600-13.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Биопсия простаты в диагностике туберкулеза предстательной железы / Е. В. Брижатюк [и др.] // Современные вопросы урологии, андрологии, репродуктивной медицины : материалы. - Новосибирск, 2008. - С. 56.</mixed-citation><mixed-citation xml:lang="en">Биопсия простаты в диагностике туберкулеза предстательной железы / Е. В. Брижатюк [и др.] // Современные вопросы урологии, андрологии, репродуктивной медицины : материалы. - Новосибирск, 2008. - С. 56.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Кульчавеня Е. В. Простатит. Диагностика и лечение : руководство / Е. В. Кульчавеня, А. И. Неймарк. - М. : ГЭОТАР-Медиа, 2010. - 256 с. (Библиотека врача-специалиста).</mixed-citation><mixed-citation xml:lang="en">Кульчавеня Е. В. Простатит. Диагностика и лечение : руководство / Е. В. Кульчавеня, А. И. Неймарк. - М. : ГЭОТАР-Медиа, 2010. - 256 с. (Библиотека врача-специалиста).</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Щербань М. Н. Диагностика, предупреждение и лечение нарушений репродуктивной функции у мужчин, больных туберкулёзом лёгких / М. Н. Щербань, Е. В. Кульчавеня, Е. В. Брижатюк // Туберкулёз и болезни лёгких. - 2010. - № 10. - С. 31-36.</mixed-citation><mixed-citation xml:lang="en">Щербань М. Н. Диагностика, предупреждение и лечение нарушений репродуктивной функции у мужчин, больных туберкулёзом лёгких / М. Н. Щербань, Е. В. Кульчавеня, Е. В. Брижатюк // Туберкулёз и болезни лёгких. - 2010. - № 10. - С. 31-36.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kholtobin D. Prostate biopsy for diagnosis of prostate tuberculosis / D. Kholtobin, E. Kulchavenya, E. Brizhatyuk // ERS annual Congress, Amsterdam, 2011. - 496 s.</mixed-citation><mixed-citation xml:lang="en">Kholtobin D. Prostate biopsy for diagnosis of prostate tuberculosis / D. Kholtobin, E. Kulchavenya, E. Brizhatyuk // ERS annual Congress, Amsterdam, 2011. - 496 s.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kulchavenya E. Urogenital Tuberculosis : Epidemiology, Diagnosis, Therapy [electron resource] / E. Kulchavenya // Springer : Cham, Heidelberg, New York, Dordrecht, London, 2014. - 137 p. - Access mode : (http://www.springer.com/us/book/9783319048369). - Access date : 10.09.2015.</mixed-citation><mixed-citation xml:lang="en">Kulchavenya E. Urogenital Tuberculosis : Epidemiology, Diagnosis, Therapy [electron resource] / E. Kulchavenya // Springer : Cham, Heidelberg, New York, Dordrecht, London, 2014. - 137 p. - Access mode : (http://www.springer.com/us/book/9783319048369). - Access date : 10.09.2015.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Seminal, ultrasound and psychobiological parameters correlate with metabolic syndrome in male members of infertile couples / F. Lotti [et al.] // Andrology. - 2013. - Vol. 1. - Р. 229-39.</mixed-citation><mixed-citation xml:lang="en">Seminal, ultrasound and psychobiological parameters correlate with metabolic syndrome in male members of infertile couples / F. Lotti [et al.] // Andrology. - 2013. - Vol. 1. - Р. 229-39.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Тюзиков И. А. Особенности персистенции инфекции предстательной железы у мужчин с сахарным диабетом / И. А. Тюзиков // Андрология и генитальная хирургия. - 2011. - № 2. - С. 30-34.</mixed-citation><mixed-citation xml:lang="en">Тюзиков И. А. Особенности персистенции инфекции предстательной железы у мужчин с сахарным диабетом / И. А. Тюзиков // Андрология и генитальная хирургия. - 2011. - № 2. - С. 30-34.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Adipocytokines and the metabolic syndrome among older persons with and without obesity : the InCHIANTI study [electron resource] / S. Stenholm [et al.] // Clin. Endocrinol. (Oxf). - 2010 Jul. - Vol. 73 (1). - Р. 55-65. - Access mode : (http://www.researchgate.net/publication/38056811_Adipocytokines_and_the_ metabolic_syndrome_among_older_persons_with_and_without_obesity_-_the_InCHIANTI_Study). - Access date : 10.09.2015.</mixed-citation><mixed-citation xml:lang="en">Adipocytokines and the metabolic syndrome among older persons with and without obesity : the InCHIANTI study [electron resource] / S. Stenholm [et al.] // Clin. Endocrinol. (Oxf). - 2010 Jul. - Vol. 73 (1). - Р. 55-65. - Access mode : (http://www.researchgate.net/publication/38056811_Adipocytokines_and_the_ metabolic_syndrome_among_older_persons_with_and_without_obesity_-_the_InCHIANTI_Study). - Access date : 10.09.2015.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Levels of adiponectin, C-reactive protein and interleukin-1 receptor antagonist are associated with insulin sensitivity : a population-based study / J. Saltevo [et al.] // Diabetes Metab. Res. Rev. - 2008 Jul-Aug. - Vol. 24 (5). - Р. 378-83.</mixed-citation><mixed-citation xml:lang="en">Levels of adiponectin, C-reactive protein and interleukin-1 receptor antagonist are associated with insulin sensitivity : a population-based study / J. Saltevo [et al.] // Diabetes Metab. Res. Rev. - 2008 Jul-Aug. - Vol. 24 (5). - Р. 378-83.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kalyani R. R. Androgen deWciency, diabetes, and the metabolic syndrome in men / R. R. Kalyani, A. S. Dobs // Curr. Opin. Endocrinol. Diabetes Obes. - 2007. - Vol. 14. - Р. 226-234.</mixed-citation><mixed-citation xml:lang="en">Kalyani R. R. Androgen deWciency, diabetes, and the metabolic syndrome in men / R. R. Kalyani, A. S. Dobs // Curr. Opin. Endocrinol. Diabetes Obes. - 2007. - Vol. 14. - Р. 226-234.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Kort H. I. Impact of body mass index values on sperm quantity and quality / H. I. Kort, J. B. Massey, C. W. Elsner // J. Androl. - 2006. - Vol. 27. - Р. 450-452.</mixed-citation><mixed-citation xml:lang="en">Kort H. I. Impact of body mass index values on sperm quantity and quality / H. I. Kort, J. B. Massey, C. W. Elsner // J. Androl. - 2006. - Vol. 27. - Р. 450-452.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kasturi S. S. The metabolic syndrome and male infertility / S. S. Kasturi, J. Tannir, R. E. Brannigan // J. Androl. - 2008. - Vol. 29. - Р. 251-9.</mixed-citation><mixed-citation xml:lang="en">Kasturi S. S. The metabolic syndrome and male infertility / S. S. Kasturi, J. Tannir, R. E. Brannigan // J. Androl. - 2008. - Vol. 29. - Р. 251-9.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Men’s body mass index and infertility / R. H. Nguyen [et al.] // Hum Reprod. - 2007. - Vol. 22. - Р. 2488-2493.</mixed-citation><mixed-citation xml:lang="en">Men’s body mass index and infertility / R. H. Nguyen [et al.] // Hum Reprod. - 2007. - Vol. 22. - Р. 2488-2493.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
