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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-441</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.03.00 МЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИ)</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ МЕЗЕНХИМАЛЬНЫХ СТВОЛОВЫХ КЛЕТОК НА СЫВОРОТОЧНЫЕ ПОКАЗАТЕЛИ У КРЫС ПРИ ВИБРАЦИОННО-ШУМОВОМ ВОЗДЕЙСТВИИ</article-title><trans-title-group xml:lang="en"><trans-title>THE EFFECT OF MESENCHYMAL STEM CELLS ON SERUM INDICES IN RATS DURING EXPOSURE TO VIBRATION AND NOISE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абдулкина</surname><given-names>Н. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Abdulkina</surname><given-names>N. G.</given-names></name></name-alternatives><email xlink:type="simple">nauka@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaytsev</surname><given-names>K. V.</given-names></name></name-alternatives><email xlink:type="simple">ZaycevKV@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жукова</surname><given-names>О. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhukova</surname><given-names>O. B.</given-names></name></name-alternatives><email xlink:type="simple">exper@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гостюхина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gostyukhina</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">exper@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воробьев</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vorobyev</surname><given-names>V. A.</given-names></name></name-alternatives><email xlink:type="simple">kb81@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зайцев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaytsev</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">niikf@med.tomsk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Сибирский федеральный научно-клинический центр Федерального медико-биологического агентства»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Budgetary Institution «The Siberian Federal Research Clinical Center under the Federal Medical Biological Agency»</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2018</year></pub-date><volume>0</volume><issue>4</issue><fpage>9</fpage><lpage>9</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Абдулкина Н.Г., Зайцев К.В., Жукова О.Б., Гостюхина А.А., Воробьев В.А., Зайцев А.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Абдулкина Н.Г., Зайцев К.В., Жукова О.Б., Гостюхина А.А., Воробьев В.А., Зайцев А.А.</copyright-holder><copyright-holder xml:lang="en">Abdulkina N.G., Zaytsev K.V., Zhukova O.B., Gostyukhina A.A., Vorobyev V.A., Zaytsev A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/441">https://jsms.elpub.ru/jour/article/view/441</self-uri><abstract><p>Проведенное исследование было посвящено экспериментальному обоснованию возможности коррекции нарушений при моделировании длительного воздействия повышенных уровней общей вибрации и шума у крыс с помощью клеточных технологий. Полученные результаты продемонстрировали положительные изменения уровней кортикостерона и нейронспецифической енолазы при введении мезенхимальных стволовых клеток на фоне длительного вибрационно-шумового воздействия.</p></abstract><trans-abstract xml:lang="en"><p>The study is devoted to experimental evidence that justifies a possibility to correct damage after the simulation of prolonged exposure to high levels of whole-body vibration and noise in rats by using cell technologies. The research findings demonstrate positive changes in levels of corticosterone and neuron specific enolase when mesenchymal stem cells are administered to animals affected by prolonged exposure to vibration and noise.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>производственная вибрация</kwd><kwd>производственный шум</kwd><kwd>мезенхимальные стволовые клетки</kwd><kwd>эксперимент</kwd><kwd>кортикостерон</kwd><kwd>нейронспецифическая енолаза</kwd><kwd>креатинин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>industrial vibration</kwd><kwd>industrial noise</kwd><kwd>mesenchymal stem cells</kwd><kwd>experiment</kwd><kwd>corticosterone</kwd><kwd>neuron specific enolase</kwd><kwd>creatinine</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бесько В. А. Организация медицинского обслуживания работников ЛПУ : производственный принцип / В. А. 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