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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-507</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Комплексное лечение экссудативного отита</article-title><trans-title-group xml:lang="en"><trans-title>Comprehensive treatment of the exudative otitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Опре</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Opre</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">opreanastasiya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андамова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Andamova</surname><given-names>O. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселёв</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России; ГБУЗ НСО «Городская клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; City Clinical Hospital No. 1. (Novosibirsk)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>04</day><month>12</month><year>2018</year></pub-date><volume>0</volume><issue>3</issue><fpage>53</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Опре А.Е., Андамова О.В., Киселёв А.Б., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Опре А.Е., Андамова О.В., Киселёв А.Б.</copyright-holder><copyright-holder xml:lang="en">Opre A.E., Andamova O.V., Kiselev A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/507">https://jsms.elpub.ru/jour/article/view/507</self-uri><abstract><p>Экссудативный отит является одним из наиболее распространенных заболеваний среднего уха. На сегодняшний день клиническая картина данного заболевания зачастую скудна, что обусловливает трудности в диагностике и своевременном назначении лечения. Традиционная терапия включает системные и местные противоотечные препараты, в то время как в данной статье продемонстрирована клиническая эффективность интраназальных глюкокортикостероидов в лечении данной патологии, поскольку в основе этиопатогенеза этого вида отита лежит развитие назальной обструкции, обусловленной не только вазомоторным, но и аллергическим компонентом. Результаты, полученные в ходе исследования, позволяют рекомендовать схему комплексного лечения экссудативного отита с использованием местного лечения, а также системной противовоспалительной, десенсибилизирующей, муколитической и противоотечной терапией для широкого практического применения в оториноларингологической практике.</p></abstract><trans-abstract xml:lang="en"><p>Exudative otitis is one of the most common diseases of the middle ear. To date, the clinical picture of this disease is often dim, which makes it difficult to diagnose and provide timely treatment. Traditional therapy includes systemic and local decongestants, while this paper demonstrates the clinical efficacy of intranasal glucocorticosteroids in the treatment of this pathology, since the etiopathogenesis of this type of otitis is based on the development of nasal obstruction caused not only by the vasomotor, but also by the allergic component. The results obtained make it possible to recommend a scheme for the complex treatment of exudative otitis using local treatment, as well as systemic anti-inflammatory, desensitizing, mucolytic and decongestant therapy for wide practical use in otorhinolaryngological practice.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>экссудативный отит</kwd><kwd>лечение</kwd><kwd>консервативная терапия средних отитов</kwd><kwd>интраназальные глюкокортикостероиды</kwd></kwd-group><kwd-group xml:lang="en"><kwd>exudative otitis</kwd><kwd>treatment</kwd><kwd>conservative therapy of otitis media</kwd><kwd>intranasal glucocorticosteroids</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Вишняков В.В., Синьков Э.В., Саракуева А.Р. Современные методы диагностики и лечения больных с экссудативным средним отитом // Материалы 2-го Петербургского форума оториноларингологов России. 2013. С. 44-46.</mixed-citation><mixed-citation xml:lang="en">Вишняков В.В., Синьков Э.В., Саракуева А.Р. Современные методы диагностики и лечения больных с экссудативным средним отитом // Материалы 2-го Петербургского форума оториноларингологов России. 2013. С. 44-46.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Tos M., Poulsen G., Borch J. Etiologic factors in secretory otitis // Arch. Otolaryngology. 2011. Vol. 105 (10). P. 582-588.</mixed-citation><mixed-citation xml:lang="en">Tos M., Poulsen G., Borch J. Etiologic factors in secretory otitis // Arch. Otolaryngology. 2011. Vol. 105 (10). P. 582-588.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Магомедов М.М., Никитина А.Ю., Левина Ю.В., Красюк А.А., Утешева В.А. Экссудативный средний отит. Современные представления и актуальность проблемы // Вестн. оториноларингологии. 2012. № 5. С. 93-97.</mixed-citation><mixed-citation xml:lang="en">Магомедов М.М., Никитина А.Ю., Левина Ю.В., Красюк А.А., Утешева В.А. Экссудативный средний отит. Современные представления и актуальность проблемы // Вестн. оториноларингологии. 2012. № 5. С. 93-97.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kim S.H., Jeon E.J., Hong S.M. Bacterial species and antibiotic sensitivity in korean patients diagnosed with acute otitis media and otitis media with effusion // J. Korean Med. Sci. 2017, Apr. 32(4). P. 672-678.</mixed-citation><mixed-citation xml:lang="en">Kim S.H., Jeon E.J., Hong S.M. Bacterial species and antibiotic sensitivity in korean patients diagnosed with acute otitis media and otitis media with effusion // J. Korean Med. Sci. 2017, Apr. 32(4). P. 672-678.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Кунельская Н.Л., Ивойлов А.Ю., Пакина В.Р., Яновский В.В. Экссудативный средний отит в детском возрасте // Вестн. оториноларингологии. 2015. № 1. С. 75-79.</mixed-citation><mixed-citation xml:lang="en">Кунельская Н.Л., Ивойлов А.Ю., Пакина В.Р., Яновский В.В. Экссудативный средний отит в детском возрасте // Вестн. оториноларингологии. 2015. № 1. С. 75-79.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Berkman N.D., Wallace I.F., Steiner M.J. et al. Otitis media with effusion: comparative effectiveness of treatments / Rockville (MD): Agency for Healthcare Research and Quality (US). 2013, May. Report No. 13: EHCO91-EF.</mixed-citation><mixed-citation xml:lang="en">Berkman N.D., Wallace I.F., Steiner M.J. et al. Otitis media with effusion: comparative effectiveness of treatments / Rockville (MD): Agency for Healthcare Research and Quality (US). 2013, May. Report No. 13: EHCO91-EF.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Li S., Zhang H., Wei Y., Zhang X. Clinical comparative study on the treatment characteristics of secretory otitis media between cleft and non-cleft palate patients // Hua Xi Kou Qiang Yi Xue Za Zhi. 2015, Jun. 33(3). P. 259-262.</mixed-citation><mixed-citation xml:lang="en">Li S., Zhang H., Wei Y., Zhang X. Clinical comparative study on the treatment characteristics of secretory otitis media between cleft and non-cleft palate patients // Hua Xi Kou Qiang Yi Xue Za Zhi. 2015, Jun. 33(3). P. 259-262.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Son M.J., Choi S., Kim Y.E., Kim Y.H. Herbal medicines for the treatment of otitis media with effusion: a systematic review of randomised controlled trials // BMJ Open. 2016, Nov. 6(11) P. 154-157.</mixed-citation><mixed-citation xml:lang="en">Son M.J., Choi S., Kim Y.E., Kim Y.H. Herbal medicines for the treatment of otitis media with effusion: a systematic review of randomised controlled trials // BMJ Open. 2016, Nov. 6(11) P. 154-157.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">El-Anwar M.W., Amer H.S., Elnashar I., Khazbak A.O., Khater A. Effect of сentral inset pharyngeal flap for velopharyngeal insufficiency on eustachian tube function laryngoscope // Laryngoscope. 2015, Jul. 125(7). P. 1729-1732.</mixed-citation><mixed-citation xml:lang="en">El-Anwar M.W., Amer H.S., Elnashar I., Khazbak A.O., Khater A. Effect of сentral inset pharyngeal flap for velopharyngeal insufficiency on eustachian tube function laryngoscope // Laryngoscope. 2015, Jul. 125(7). P. 1729-1732.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Yousaf M., Inayatullah Khan F. Medical versus surgical management of otitis media with effusion in children // J. Ayub Med. Coll. Abbottabad. 2012. Vol. 24(1). P. 83-85.</mixed-citation><mixed-citation xml:lang="en">Yousaf M., Inayatullah Khan F. Medical versus surgical management of otitis media with effusion in children // J. Ayub Med. Coll. Abbottabad. 2012. Vol. 24(1). P. 83-85.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
