<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31549/2542-1174-2019-1-18-27</article-id><article-id custom-type="elpub" pub-id-type="custom">jsms-553</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Состояние овариального резерва у пациенток с функциональными кистами яичников</article-title><trans-title-group xml:lang="en"><trans-title>The state of ovarian reserve in patients with functional ovarian cysts</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волченок</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volchenok</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Волченок Дарья Александровна — аспирант кафедры гистологии, эмбриологии и цитологии.</p><p>634050, Томск, Московский тракт, 2.</p></bio><bio xml:lang="en"><p>Volchenok Daria Aleksandrovna — Graduate Student of the Department of  Histology,  Embriology and Cytology.</p><p>2, Moskovsky Trakt, Tomsk, 634050.</p></bio><email xlink:type="simple">daria.trus.2017@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихоновская</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tikhonovskaya</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тихоновская Ольга Анатольевна — доктор медицинских наук, профессор кафедры акушерства и гинекологии.</p><p>634050, Томск, Московский тракт, 2.</p></bio><bio xml:lang="en"><p>Tikhonovskaya Olga Anatolyevna — Dr. Sci. (Med.), Professor of the Department of Obstetrics and Gynecology.</p><p>2, Moskovsky Trakt, Tomsk, 634050.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Илья Алексеевич — доктор медицинских наук, профессор кафедры акушерства и гинекологии.</p><p>634050, Томск, Московский тракт, 2.</p></bio><bio xml:lang="en"><p>Petrov Ilya Alekseevich — Dr. Sci. (Med.), Professor of the Department of Obstetrics and Gynecology.</p><p>2, Moskovsky Trakt, Tomsk, 634050.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Логвинов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Logvinov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Логвинов Сергей Валентинович — доктор медицинских наук, профессор, заведующий кафедрой гистологии, эмбриологии и цитологии.</p><p>634050, Томск, Московский тракт, 2.</p></bio><bio xml:lang="en"><p>Logvinov Sergey Valentinovich — Dr. Sci. (Med.), Professor, Head of the Department of Histology, Embriology and Cytology.</p><p>2, Moskovsky Trakt, Tomsk, 634050.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мунгалова</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Mungalova</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мунгалова  Анастасия  Дмитриевна  —  ординатор кафедры акушерства и гинекологии.</p><p>634050, Томск, Московский тракт, 2.</p></bio><bio xml:lang="en"><p>Mungalova Anastasia Dmitrievna — Resident of the Department of Obstetrics and Gynecology.</p><p>2, Moskovsky Trakt, Tomsk, 634050.</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Сибирский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>25</day><month>07</month><year>2019</year></pub-date><volume>0</volume><issue>1</issue><fpage>18</fpage><lpage>27</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Волченок Д.А., Тихоновская О.А., Петров И.А., Логвинов С.В., Мунгалова А.Д., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Волченок Д.А., Тихоновская О.А., Петров И.А., Логвинов С.В., Мунгалова А.Д.</copyright-holder><copyright-holder xml:lang="en">Volchenok D.A., Tikhonovskaya O.A., Petrov I.A., Logvinov S.V., Mungalova A.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/553">https://jsms.elpub.ru/jour/article/view/553</self-uri><abstract><p>В исследование, посвященное изучению показателей овариального резерва у пациенток с функциональными кистами яичников (ФКЯ), включены 137 пациенток с бесплодием и хирургическим лечением ФКЯ в анамнезе. Проведен ретроспективный анализ историй болезни, проспективно определены показатели функционального овариального резерва: сывороточные значения антимюллерова гормона и фолликулостимулирующего гормона, ингибина В, эстрадиола; объем яичников, число антральных фолликулов (ФАС) при сонографии на 2–3-й день менструального цикла. Основную группу (n = 53) составили пациентки, отвечающие Болонским критериям бедного ответа, принятым Европейским обществом репродукции человека и эмбриологии (ESHRE, 2011); группу сравнения — женщины с хорошим ответом на контролируемую индукцию овуляции (n = 84). Контроль — условно здоровые женщины (n = 15).</p><p>Наиболее выраженное снижение овариального резерва выявлено при осложненном клиническом течении ФКЯ (разрыв, кровоизлияние). Снижение показателей овариального резерва наблюдалось у пациенток с повторными инвазивными вмешательствами на яичниках, спаечным процессом 3-й и 4-й степени, а также с сопутствующими воспалительными процессами органов малого таза в виде хронического сальпингита.</p></abstract><trans-abstract xml:lang="en"><p>The study of ovarian reserve indices in patients with functional ovarian cysts (FOC) included 137 patients with infertility and surgical treatment of functional ovarian cysts in history. A retrospective analysis of medical histories was carried out, the indicators of functional ovarian reserve were prospectively determined: serum values of Anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH), inhibin B, estradiol; volume of ovaries, ovarian antral follicle count (AFC) at sonography on the 2nd–3rd day of the menstrual cycle. The main group (n = 53) consisted of patients who met the Bologna criteria for poor response adopted by the European Society of Human Reproduction and Embryology (ESHRE, 2011); the comparison group consisted of women with a good response to the controlled induction of ovulation (n = 84). Control — conditionally healthy women (n = 15).</p><p>The most pronounced decrease in ovarian reserve was revealed in complicated clinical course of FOC (rupture, hemorrhage). Reduction of ovarian reserve indices was observed in patients with repeated invasive interventions on the ovaries, adhesive process of the 3rd and 4th degree, as well as with concomitant inflammatory processes of the pelvic organs in the form of chronic salpingitis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональные кисты яичников</kwd><kwd>овариальный резерв</kwd><kwd>бедный ответ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional ovarian cysts</kwd><kwd>ovarian reserve</kwd><kwd>poor response</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гасымова Д.М., Рухляда Н.Н. Клинико-анамнестические особенности пациенток с осложнениями доброкачественных опухолей и опухолевидных образований яичников // Рос. вестн. акушера-гинеколога. 2017. Т. 17, № 4. С. 72–77. doi: 10.17116/rosakush201717472-77.</mixed-citation><mixed-citation xml:lang="en">Gasymova D.M., Rukhlyada N.N. (2017). Clinical and anamnestic characteristics of patients with complications of benign tumors and tumor-like masses of the ovary. Russ. Bull. Obstetrics-Gynecology, 17, 4, 72–77. doi: 10.17116/rosakush201717472-77.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Abduljabbar H.S., Bukhari Y.A., Al Hachim E.G. et al. Review of 244 cases of ovarian cysts // Saudi Med. J. 2015. Vol. 36 (7). P. 834–838.</mixed-citation><mixed-citation xml:lang="en">Abduljabbar H.S., Bukhari Y.A., Al Hachim E.G. et al. (2015). Review of 244 cases of ovarian cysts. Saudi Med. J., 36, 7, 834–838.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Никогосян С.О., Кузнецов В.В., Загаштоков А.З. Экстренное и плановое лечение новообразований придатков матки // Акушерство и гинекология. 2017. № 6. С. 10–17. doi: 10.18565/aig.2017.6.10-6.</mixed-citation><mixed-citation xml:lang="en">Nikogosyan S.O., Kuznetsov V.V., Zagashtokov A.Z. (2017). Emergency and elective surgical management of tumors of the uterine appendages. Obstetrics and Gynecology, 6, 10–17. doi: 10.18565/aig.2017.6.10-6.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Каримов З.Д., Исмаилова Ф.Т., Хусонходжаева М.Т., Азимова Ф.М. Стратегия и тактика лечения опухолевидных образований яичников в ургентной гинекологии // Акушерство и гинекология. 2012. № 5. С. 93–96.</mixed-citation><mixed-citation xml:lang="en">Karimov  Z.D.,  Ismailova  F.I.,  Khusonkhodzhayeva M.T., Azimova F.M. (2012). Treatment strategy and tactics for ovarian tumor-like lesions in urgent gynecology. Obstetrics and Gynecology, 5, 93–96.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Farghaly S.A. Current diagnosis and management of ovarian cysts // Clin. Exp. Obstet. Gynecol. 2014. Vol. 41 (6). P. 609–612.</mixed-citation><mixed-citation xml:lang="en">Farghaly  S.A.  (2014).  Current  diagnosis  and management of ovarian cysts. Clin. Exp. Obstet. Gynecol., 41, 6, 609–612.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Гасымова Д.М., Рухляда Н.Н. Состояние репродуктивной системы у женщин после хирургических вмешательств на яичниках // Забайкальский мед. вестн. 2014. № 3. С. 117–126.</mixed-citation><mixed-citation xml:lang="en">Gasymova  D.M.,  Rukhliada  N.N.  (2014).  State  of the female reproductive system after surgery on the ovaries.  Transbaikalian  Medical  Bull.,  3,  117–126. In Russ.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Меджидова К.К., Алиева Х.Г., Гасанова М.А. и др. Лечение кист яичника // Проблемы репродукции. 2014. № 5. С. 35–38.</mixed-citation><mixed-citation xml:lang="en">Medjidova K.K., Alieva Сh.G., Gasanova M.A. et al. (2014). The treatment of the ovarian cysts. Russ. J. Human Reprod., 5, 35–38.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Kim J.H., Lee S.M., Lee J.-H. et al. Successful conservative management of ruptured ovarian cysts with hemoperitoneum in healthy women // PLoSOne. 2014. Vol. 9 (3): e91171. doi: 10.1371/journal.pone.0091171.</mixed-citation><mixed-citation xml:lang="en">Kim J.H., Lee S.M., Lee J.-H. et al. (2014). Successful conservative management of ruptured ovarian cysts with hemoperitoneum in healthy women. PLoSOne, 9, 3: e91171. doi: 10.1371/journal.pone.0091171.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ye X., Yang Y., Sun X. A retrospective analysis of the effect of salpingectomy on serum antiMüllerian hormone level and ovarian reserve // Am. J. Obstet. Gynecol. 2015. Vol. 212 (1): 53.e1-53.e10. doi: 10.1016/j.ajog.2014.07.027.</mixed-citation><mixed-citation xml:lang="en">Ye   X.,   Yang   Y.,   Sun   X.   (2015).   A   retrospective analysis of the effect of salpingectomy on serum antiMüllerian hormone level and ovarian reserve. Am. J. Obstet. Gynecol., 212, 1: 53.e1-53.e10. doi: 10.1016/j.ajog.2014.07.027.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Петров И.А., Тихоновская О.А., Куприянова И.И. и др. Механизмы вторичной недостаточности яичников при операциях на органах малого таза (экспериментальное исследование) // Акушерство, гинекология и репродукция. 2015. Т. 9, № 4. С. 6–17.</mixed-citation><mixed-citation xml:lang="en">Petrov I.A., Tikhonovskaja O.A., Kuprijanova I.I. et al. (2015). The mechanisms of secondary ovarian failure at operations on the pelvic organs (experimental study). Obstetrics, Gynecology and Reproduction, 9, 4, 6–17.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Гаспаров А.С., Дубинская Е.Д., Титов Д.С., Лаптева Н.В. Клиническое значение овариального резерва в реализации репродуктивной функции // Акушерство и гинекология. 2014. № 4. С. 11–16.</mixed-citation><mixed-citation xml:lang="en">Gasparov A.S., Dubinskaya E.D., Titov D.S., Lapteva N.V. (2014). Сlinical value of the ovarian reserve in reproductive function. Obstetrics and Gynecology, 4, 11–16.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
