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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-571</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Качество жизни больных профессиональной хронической обструктивной болезнью легких в зависимости от ее фенотипа</article-title><trans-title-group xml:lang="en"><trans-title>Quality of life in occupational chronic obstructive pulmonary disease patients with different disease phenotype</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпагина</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpagina</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Shpagina Lyubov Anatolyevna — Dr. Sci. (Med.), Professor, Head of the Internal Medicine and Medical Rehabilitation Department, NSMU; Head Physician, CCH No. 2</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Котова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Kotova</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Котова Ольга Сергеевна — кандидат медицинских наук, доцент кафедры госпитальной терапии и медицинской реабилитации НГМУ; врач-терапевт ГКБ № 2.</p><p>630091, Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Kotova Olga Sergeevna — Cand. Sci. (Med.), Associate Professor of the Internal Medicine and Medical Rehabilitation Department, NSMU; Therapeutist, CCH No. 2.</p><p>52, Krasny Prospect, Novosibirsk, 630091</p></bio><email xlink:type="simple">ok526@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шпагин</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shpagin</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Shpagin Ilya Semenovich — Dr. Sci. (Med.), Teaching Assistant of the Internal Medicine, Hematology and Transfusiology Department, NSMU</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>Г. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>G. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Kuznetsova Galina Vladimirovna — Cand. Sci. (Med.), Teaching Assistant of the Internal Medicine and Medical Rehabilitation Department, NSMU; Head of the Occupational Pathology Department, CCH No. 2</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Камнева</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kamneva</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"><p>Kamneva Natalya Vadimovna — Post-graduate Student of the Internal Medicine and Medical Rehabilitation Department, NSMU; Occupational Physician, CCH No. 2</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России; ГБУЗ НСО Городская клиническая больница № 2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; Novosibirsk City Clinical Hospital No. 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>27</day><month>07</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>24</fpage><lpage>32</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шпагина Л.А., Котова О.С., Шпагин И.С., Кузнецова Г.В., Камнева Н.В., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Шпагина Л.А., Котова О.С., Шпагин И.С., Кузнецова Г.В., Камнева Н.В.</copyright-holder><copyright-holder xml:lang="en">Shpagina L.A., Kotova O.S., Shpagin I.S., Kuznetsova G.V., Kamneva N.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/571">https://jsms.elpub.ru/jour/article/view/571</self-uri><abstract><p>В исследовании, изучавшем особенности качества жизни больных профессиональной хронической обструктивной болезнью легких (ХОБЛ), приняли участие больные профессиональной ХОБЛ, работавшие с токсичными газами/жидкостными аэрозолями (n = 55) или неорганической пылью (n = 101). Группу сравнения составили больные ХОБЛ вследствие табакокурения (n = 103). Диагноз ХОБЛ устанавливался на основании критериев GOLD 2011-2018. Качество жизни оценивали согласно анкете St. George’s Respiratory Questionnaire. Выявлено преимущественное снижение качества жизни больных профессиональной ХОБЛ, обусловленной воздействием токсичных газов/жидкостных аэрозолей, за счет влияния на физическую активность и социальные функции. Качество жизни больных профессиональной ХОБЛ снижено в большей степени, чем при ХОБЛ вследствие табакокурения.</p></abstract><trans-abstract xml:lang="en"><p>The study of the quality of life of patients with occupational chronic obstructive pulmonary disease (COPD), involved occupational COPD patients exposed to toxic gases/liquid aerosols (n = 55) or inorganic dust (n = 101). The comparison group consisted of patients with COPD due to tobacco smoking (n = 103). The diagnosis of COPD was established on the basis of the GOLD 2011-2018 criteria. Quality of life was assessed according to the St. George’s Respiratory Questionnaire. We revealed a predominant decrease in the quality of life of patients with occupational COPD due to the effects of toxic gases/liquid aerosols on account of the impact on physical activity and social functions. The quality of life of patients with COPD is reduced to a greater extent than in COPD due to smoking.       </p></trans-abstract><kwd-group xml:lang="ru"><kwd>профессиональная хроническая обструктивная болезнь легких</kwd><kwd>фенотип</kwd><kwd>промышленный аэрозоль</kwd></kwd-group><kwd-group xml:lang="en"><kwd>occupational chronic obstructive pulmonary disease</kwd><kwd>phenotype</kwd><kwd>industrial aerosol</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено при финансовой поддержке РФФИ и Министерства образования, науки и инновационной политики Новосибирской области в рамках научного проекта № 17-44-540009 р_а</funding-statement><funding-statement xml:lang="en">The study was carried out with the financial support of the Russian Foundation for Basic Research and the Ministry of Education, Science and Innovation Policy of the Novosibirsk Region as a part of the research project No. 17-44-540009 p_a</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chuchalin A.G. 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