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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-576</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Состояние полости рта у пациентов с сахарным диабетом типа MODY</article-title><trans-title-group xml:lang="en"><trans-title>The condition of the oral cavity in patients with MODY type diabetes mellitus</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрова Татьяна Геннадьевна — доктор медицинских наук, профессор, заведующий кафедрой терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Petrova Tatyana Gennadyevna — Dr. Sci. (Med.), Professor, Head of the Therapeutic Dentistry Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морева</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Moreva</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морева Нина Андреевна — кандидат медицинских наук, доцент кафедры терапевтической стоматологии</p></bio><bio xml:lang="en"><p>Moreva Nina Andreyevna — Cand. Sci. (Med.), Associate Professor of the Therapeutic Dentistry Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рымар</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Rymar</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рымар Софья Дмитриевна — студентка стоматологического факультета.</p><p>630091, Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Rymar Sofya Dmitrievna — Student of the Dental Faculty.</p><p>52, Krasny Prospect, Novosibirsk, 630091</p></bio><email xlink:type="simple">orymar23@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Овсянникова</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Ovsyannikova</surname><given-names>A. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Овсянникова Алла Константиновна — кандидат медицинских наук, научный сотрудник лаборатории клиникопопуляционных и профилактических исследований терапевтических и эндокринных заболеваний.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Ovsyannikova Alla Konstantinovna — Cand. Sci. (Med.), Researcher of the Laboratory of Clinical Population and Preventive Studies of Therapeutic and Endocrine Diseases.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рымар</surname><given-names>О. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Rymar</surname><given-names>O. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рымар Оксана Дмитриевна — доктор медицинских наук, заведующий лабораторией клинико-популяционных и профилактических исследований терапевтических и эндокринных заболеваний.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Rymar Oksana Dmitriyevna — Dr. Sci. (Med.), Head of the Laboratory of Clinical Population and Preventive Studies of Therapeutic and Endocrine Diseases.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>НИИ терапии и профилактической медицины — филиал ФГБНУ Федеральный исследовательский центр Институт цитологии и генетики СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Internal and Preventive Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>27</day><month>07</month><year>2019</year></pub-date><volume>0</volume><issue>3</issue><fpage>74</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петрова Т.Г., Морева Н.А., Рымар С.Д., Овсянникова А.К., Рымар О.Д., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Петрова Т.Г., Морева Н.А., Рымар С.Д., Овсянникова А.К., Рымар О.Д.</copyright-holder><copyright-holder xml:lang="en">Petrova T.G., Moreva N.A., Rymar S.D., Ovsyannikova A.K., Rymar O.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/576">https://jsms.elpub.ru/jour/article/view/576</self-uri><abstract><p>В исследовании, посвященном оценке стоматологического статуса у пациентов с редкой формой диабета — MODY, приняли участие 9 чел. (3 женщины и 6 мужчин). Диагноз MODY-диабета им был поставлен на основании результатов молекулярно-генетического исследования. У обследованных с разными подтипами (2, 6 и 12) MODY-диабета выявлена высокая интенсивность кариеса, воспалительных заболеваний пародонта и зубочелюстных аномалий, что существенно не влияло на качество жизни обследованных. В полости рта у больных MODY-диабетом подтипа 2 отсутствовали выраженные специфические проявления нарушений углеводного обмена, что, вероятно, может быть связано с хорошей компенсацией диабета. Также представлено клиническое описание MODY-диабета подтипа 2 у представителей двух поколений — отца и сына.</p></abstract><trans-abstract xml:lang="en"><p>In a study on the assessment of dental status in patients with a rare form of diabetes — MODY, 9 people were involved (3 women and 6 men). The diagnosis of MODY was based on the results of molecular genetic research. In patients with different subtypes (2, 6 and 12) of MODY a high intensity of caries, inflammatory periodontal diseases and dental anomalies was detected, which did not significantly affect the quality of life of the patients. In the oral cavity of patients with MODY subtype 2 there were no pronounced specific manifestations of disorders of carbohydrate metabolism, which probably can be associated with good diabetes compensation. Clinical descriptions of MODY subtype 2 in representatives of two generations — father and son — is also presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>MODY-диабет</kwd><kwd>стоматологический статус</kwd><kwd>гликированный гемоглобин</kwd><kwd>кариес</kwd><kwd>индекс гингивита</kwd><kwd>индекс пародонтита</kwd></kwd-group><kwd-group xml:lang="en"><kwd>MODY</kwd><kwd>dental status</kwd><kwd>glycated hemoglobin</kwd><kwd>caries</kwd><kwd>gingivitis index</kwd><kwd>periodontitis index</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Cho N.H., Shaw J.E., Karuranda S. et al. IDF diabetes atlas: Global estimates of diabetes prevalence for 2017 and projections for 2045 // Diabetes Res. Clin. Pract. 2018. Vol. 138. P. 271-281. doi: 10.1016/j.diabres.2018.02.023.</mixed-citation><mixed-citation xml:lang="en">Cho N.H., Shaw J.E., Karuranda S. et al. (2018). 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