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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31549/2542-1174-2020-1-55-64</article-id><article-id custom-type="elpub" pub-id-type="custom">jsms-613</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Структурно-функциональное состояние сердца у больных пожилого возраста с сочетанной бронхообструктивной патологией и артериальной гипертензией</article-title><trans-title-group xml:lang="en"><trans-title>Structural and functional state of the heart in elderly patients with combined broncho-obstructive pathology and arterial hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Третьяков</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tretyakov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Третьяков Сергей Владиславович — д-р мед. наук, профессор кафедры поликлинической терапии и общей медицинской практики</p><p>630091, г. Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Tretyakov Sergey Vladislavovich — Dr. Sci. (Med.), Professor, Department of Polyclinic Therapy and General Medical Practice</p><p>52, Krasny Prospect, Novosibirsk, 630091</p></bio><email xlink:type="simple">ser53953824@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Popova</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попова Анна Александровна — д-р мед. наук, доцент, заведующий кафедрой поликлинической терапии и общей медицинской практики</p></bio><bio xml:lang="en"><p>Popova Anna Aleksandrovna — Dr. Sci. (Med.), Assistant Professor, Head, Department of Polyclinic Therapy and General Medical Practice</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дёмин</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Demin</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дёмин Александр Аристархович — д-р мед. наук, профессор, заведующий кафедрой госпитальной терапии</p></bio><bio xml:lang="en"><p>Demin Aleksandr Aristarkhovich — Dr. Sci. (Med.), Professor, Head, Department of Hospital Therapy</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2020</year></pub-date><volume>0</volume><issue>1</issue><fpage>55</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Третьяков С.В., Попова А.А., Дёмин А.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Третьяков С.В., Попова А.А., Дёмин А.А.</copyright-holder><copyright-holder xml:lang="en">Tretyakov S.V., Popova A.A., Demin A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/613">https://jsms.elpub.ru/jour/article/view/613</self-uri><abstract><p>С целью уточнения особенностей структурно-функционального состояния сердца при сочетании хронической обструктивной болезни легких (ХОБЛ) и бронхиальной астмы (БА) у лиц пожилого возраста с артериальной гипертензией (АГ) проведено данное исследование. Обследовано 15 мужчин с ХОБЛ и БА (средний возраст — 68.4 ± 3.6 г.). Группу сравнения составили 15 больных ХОБЛ (средний возраст — 63.4 ± 3.2 г.). У всех лиц ХОБЛ была категории В.Выявлено, что при сочетанной бронхообструктивной патологии, в отличие от больных с ХОБЛ, у лиц пожилого возраста с АГ отмечается большая степень выраженности концентрической гипертрофии левого желудочка при повышении его контрактильности (а именно глобальной продольной систолической способности) на фоне отсутствия отличий по диастолической его функции и, в частности, продольной. При сочетании ХОБЛ и БА, в отличие от больных с ХОБЛ, у лиц пожилого возраста с АГ отмечается большая степень нарушения активного расслабления правого желудочка при повышении его функции, в частности глобальной продольной систолической функции, на фоне более выраженной легочной гипертонии. Выявленные особенности гемодинамики малого круга кровообращения и функции правого желудочка являются основой для выбора патогенетически оправданной терапии, направленной не только на снижение давления в легочной артерии, но и на улучшение кальциевых механизмов как в систолу, так и в диастолу.</p></abstract><trans-abstract xml:lang="en"><p>In order to specify features of a structural and functional state of the heart in the combination of chronic obstructive pulmonary disease (COPD) and bronchial asthma (BA) in elderly people with arterial hypertension (AH) this research was conducted. The 15 men with COPD and BA (average age — 68.4 ± 3.6 years) were surveyed. The group of comparison consisted of 15 patients with COPD (average age — 63.4 ± 3.2 years). All patients had type B COPD.It was revealed that in the combined broncho-obstructive pathology, unlike patients with COPD, the elderly people with AH show a greater degree of concentric hypertrophy of left ventricle with an increase in its contractility (namely, global longitudinal systolic capacity) against the background of lack of differences in its diastolic function and longitudinal in particular. When COPD and BA are combined the elderly people with AH, unlike patients with COPD, have a larger degree of impaired active relaxation of the right ventricle with an increase in its function, particularly global longitudinal systolic function, against the background of more pronounced pulmonary hypertension. The revealed features of hemodynamics of pulmonary circulation and function of right ventricle are the basis for choosing pathogenetically justiﬁed therapy aimed not only at decreasing the pulmonary artery pressure, but also at improvement of calcium mechanisms in both systole and diastole.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>левый желудочек</kwd><kwd>правый желудочек</kwd><kwd>сократительная функция</kwd><kwd>диастолическая функция</kwd><kwd>хроническая обструктивная болезнь легких</kwd><kwd>бронхиальная астма</kwd></kwd-group><kwd-group xml:lang="en"><kwd>left ventricle</kwd><kwd>right ventricle</kwd><kwd>contractile function</kwd><kwd>diastolic function</kwd><kwd>chronic obstructive pulmonary disease</kwd><kwd>bronchial asthma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чучалин А.Г. 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