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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31549/2542-1174-2021-1-92-104</article-id><article-id custom-type="elpub" pub-id-type="custom">jsms-688</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Новые аспекты этиологии и патогенеза ВИЧ-инфекции (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>New aspects of the etiology and pathogenesis of HIV infection (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капустин</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapustin</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Капустин Дмитрий Вячеславович — кандидат медицинских наук, ассистент кафедры инфекционных болезней.</p><p>630091, Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Kapustin Dmitry Vyacheslavovich — Cand. Sci. (Med.), Teaching Assistant, Infectious Diseases Department.</p><p>52, Krasny Prospect, Novosibirsk, 630091</p></bio><email xlink:type="simple">geksogen08@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ульянова</surname><given-names>Я. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ul’yanova</surname><given-names>Ya. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ульянова Яна Савельевна — врач-инфекционист, заместитель главного врача.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Ul’yanova Yana Savelyevna — Infectious Disease Physician, Deputy Chief Physician</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карпович</surname><given-names>Г. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Karpovich</surname><given-names>G. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карпович Глеб Сергеевич — ассистент кафедры инфекционных болезней</p></bio><bio xml:lang="en"><p>Karpovich Gleb Sergeyevich — Teaching Assistant, Infectious Diseases Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Краснова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Krasnova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Краснова Елена Игоревна — доктор медицинских наук, профессор, заведующий кафедрой инфекционных болезней</p></bio><bio xml:lang="en"><p>Krasnova Elena Igorevna — Dr. Sci. (Med.), Professor, Head, Infectious Diseases Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>В. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>V. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Вера Гаврииловна — доктор медицинских наук, профессор кафедры инфекционных болезней</p></bio><bio xml:lang="en"><p>Kuznetsova Vera Gavriilovna — Dr. Sci. (Med.), Professor, Infectious Diseases Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Извекова</surname><given-names>И. Я.</given-names></name><name name-style="western" xml:lang="en"><surname>Izvekova</surname><given-names>I. Ya.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Извекова Ирина Яковлевна — доктор медицинских наук, профессор кафедры инфекционных болезней</p></bio><bio xml:lang="en"><p>Izvekova Irina Yakovlevna — Dr. Sci. (Med.), Professor, Infectious Diseases Department</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Новосибирский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ НСО Городская инфекционная клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Infectious Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>10</day><month>04</month><year>2021</year></pub-date><volume>0</volume><issue>1</issue><fpage>92</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Капустин Д.В., Ульянова Я.С., Карпович Г.С., Краснова Е.И., Кузнецова В.Г., Извекова И.Я., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Капустин Д.В., Ульянова Я.С., Карпович Г.С., Краснова Е.И., Кузнецова В.Г., Извекова И.Я.</copyright-holder><copyright-holder xml:lang="en">Kapustin D.V., Ul’yanova Y.S., Karpovich G.S., Krasnova E.I., Kuznetsova V.G., Izvekova I.Y.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/688">https://jsms.elpub.ru/jour/article/view/688</self-uri><abstract><p>В обзоре даны современные представления об этиологии и патогенезе ВИЧ-инфекции, освещаются вопросы иммунного ответа при данном заболевании, а также проблемы резистентности ВИЧ к современным лекарственным препаратам.</p></abstract><trans-abstract xml:lang="en"><p>The paper presents the review on current ideas about the etiology and pathogenesis of HIV infection. It highlights the issues of the immune response in this disease, as well as the problems of HIV resistance to modern drugs.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ВИЧ-инфекция</kwd><kwd>СПИД</kwd><kwd>инфекционные болезни</kwd><kwd>резистентность ВИЧ</kwd><kwd>иммунопатогенез ВИЧ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>HIV infection</kwd><kwd>AIDS</kwd><kwd>infectious diseases</kwd><kwd>HIV resistance</kwd><kwd>HIV immunopathogenesis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">World Heath Organization. HIV/AIDS. URL: https://www.who.int/health-topics/hiv-aids/. Дата обращения: 09.11.2020.</mixed-citation><mixed-citation xml:lang="en">World Health Organization. HIV/AIDS (2020). 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