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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">jsms</journal-id><journal-title-group><journal-title xml:lang="ru">Journal of Siberian Medical Sciences</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of Siberian Medical Sciences</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2542-1174</issn><publisher><publisher-name>Federal state budgetary educational institution of higher education "Novosibirsk state medical university" of  Ministry of Health of the Russian Federation (FSBEI HE NSMU MOH Russia)</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">jsms-699</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Клинико-анатомическое наблюдение первого летального исхода от коронавирусной инфекции в Новосибирской области</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and anatomical case study of the first death from the novel coronavirus infection in the Novosibirsk Region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Надеев</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Nadeev</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Надеев Александр Петрович — доктор медицинских наук, профессор, заведующий кафедрой патологической анатомии.</p><p>630091, Новосибирск, Красный просп., 52</p></bio><bio xml:lang="en"><p>Nadeev Aleksandr Petrovich — Dr. Sci. (Med.), Professor, Head, Department of Pathological Anatomy.</p><p>52, Krasny Prospect, Novosibirsk, 630091</p></bio><email xlink:type="simple">nadeevngma@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеев</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseev</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеев Андрей Юрьевич — врач-патологоанатом.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Alekseev Andrey Yuryevich — Pathologist.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Дмитрий Вильевич — кандидат медицинских наук, заведующий патолого-анатомическим отделением.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Morozov Dmitry Vilevich — Cand. Sci. (Med.), Head, Pathological and Anatomical Unit.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Травин</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Travin</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Травин Михаил Андреевич — кандидат медицинских наук, доцент кафедры патологической анатомии</p></bio><bio xml:lang="en"><p>Travin Mikhail Andreyevich — Cand. Sci. (Med.), Assistant Professor, Department of Pathological Anatomy.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельников</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Melnikov</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мельников Василий Михайлович — кандидат медицинских наук, доцент кафедры оперативной хирургии и топографической анатомии</p></bio><bio xml:lang="en"><p>Melnikov Vasiliy Michailovich — Cand. Sci. (Med.), Associate Professor, Department of Operative Surgery and Regional Anatomy.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsov</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецов Алексей Владимирович — доктор медицинских наук, доцент, заведующий кафедрой оперативной хирургии и топографической анатомии</p></bio><bio xml:lang="en"><p>Kuznetsov Aleksey Vladimirovich — Dr. Sci. (Med.), Associate Professor, Head, Department of Operative Surgery and Regional Anatomy.</p><p>Novosibirsk</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУВО Новосибирский государственный медицинский университет» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ НСО Городская клиническая больница № 1</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУВО Новосибирский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>11</day><month>04</month><year>2021</year></pub-date><volume>0</volume><issue>4</issue><fpage>99</fpage><lpage>109</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Надеев А.П., Алексеев А.Ю., Морозов Д.В., Травин М.А., Мельников В.М., Кузнецов А.В., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Надеев А.П., Алексеев А.Ю., Морозов Д.В., Травин М.А., Мельников В.М., Кузнецов А.В.</copyright-holder><copyright-holder xml:lang="en">Nadeev A.P., Alekseev A.Y., Morozov D.V., Travin M.A., Melnikov V.M., Kuznetsov А.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://jsms.elpub.ru/jour/article/view/699">https://jsms.elpub.ru/jour/article/view/699</self-uri><abstract><p>Представлено клинико-анатомическое наблюдение первого летального исхода от новой коронавирусной инфекции в Новосибирской области. Также кратко освещены вопросы этиологии, эпидемиологии COVID-19, обобщены данные по патологической анатомии при COVID-19, с акцентом на морфологические изменения в легких при пневмонии, вызванной коронавирусной инфекцией.</p></abstract><trans-abstract xml:lang="en"><p>Clinical and anatomical case study of the first death from the novel coronavirus infection in the Novosibirsk Region is presented. The matter of etiology, epidemiology COVID-19 are also briefly taken up, data on pathological anatomy in COVID-19 are generalized, with the emphasis on morphological changes in lungs in pneumonia caused by coronavirus infection.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>COVID-19</kwd><kwd>патологическая анатомия</kwd><kwd>пневмония</kwd><kwd>вскрытие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>pathological anatomy</kwd><kwd>pneumonia</kwd><kwd>autopsy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Han Y., Yang H. The transmission and diagnosis of 2019 novel coronavirus infection disease (COVID-19): A Chinese perspective // J. Med. Virol. 2020. Vol. 92 (6). P. 639-644.</mixed-citation><mixed-citation xml:lang="en">Han Y., Yang H. (2020). The transmission and diagnosis of 2019 novel coronavirus infection disease (COVID-19): A Chinese perspective. J. Med. Virol., 92 (6), 639-644.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Guo Y.R., Cao Q.D., Hong Z.S. et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak — an update on the status // Mil. Med. Res. 2020. Vol. 7 (1): 11 (2020).</mixed-citation><mixed-citation xml:lang="en">Guo Y.R., Cao Q.D., Hong Z.S. et al. (2020). The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak — an update on the status. Mil. Med. Res., 7 (1), 11 (2020).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Zhai P., Ding Y., Wu X. et al. The epidemiology, diagnosis and treatment of COVID-19 // Int. J. Antimicrob. Agents. 2020. Vol. 55 (5): 105955.</mixed-citation><mixed-citation xml:lang="en">Zhai P., Ding Y., Wu X. et al. (2020). The epidemiology, diagnosis and treatment of COVID-19. Int. J. Antimicrob. Agents, 55 (5): 105955.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Бевова М.Р., Нетесов С.В., Аульченко Ю.С. Новая коронавирусная инфекция COVID-19 // Молекулярная генетика, микробиология и вирусология. 2020. Т. 38, № 2. С. 51-58.</mixed-citation><mixed-citation xml:lang="en">Bevova N.R., Netesov S.V., Aulchenko Yu.S. (2020). New coronavirus infection COVID-19. Molecular Genetics, Microbiology and Virology, 38, 2, 51-58.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ding Y.Q., Bian X.W. Analysis of coronavirus disease-19 (COVID-19) based on SARS autopsy // Zhong-hua Bing Li Xue Za Zhi. 2020. Vol. 49 (4). P. 291-293. doi: 10.3760/cma.j.cn11215120200211-01114.</mixed-citation><mixed-citation xml:lang="en">Ding Y.Q., Bian X.W. (2020). Analysis of coronavi-rus disease-19 (COVID-19) based on SARS autopsy. Zhonghua Bing Li Xue Za Zhi, 49 (4), 291-293. doi: 10.3760/cma.j.cn11215120200211-01114.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Coronavirus disease 2019 (COVID-19). Situation Report — 83. World Health Organization. April 12, 2020. URL: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200412-sitrep-83-covid-19.pdf?sfvrsn=697ce98d_4. Дата обращения: 13.04.2020.</mixed-citation><mixed-citation xml:lang="en">Coronavirus disease 2019 (COVID-19). Situation Report — 83. World Health Organization. April 12, 2020. Retrieved April 13, 2020 from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200412-sitrep-83-covid-19.pdf?sfvrsn=697ce98d_4.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Wu Z., McGoogan J.M. Characteristics of and important lessons from the coronavirus disease 2019 (CO-VID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention // JAMA. 2020. Vol. 323 (13). P. 12391242. doi.10.1001/jama.2020.2648.</mixed-citation><mixed-citation xml:lang="en">Wu Z., McGoogan J.M. (2020). Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA, 323 (13), 1238-1242. doi.10.1001/jama.2020.2648.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Bosmuller H., Traxler S., Bitzer M. et al. The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation // Virchows Arch. 2020. Vol. 477 (3). P. 349-357. doi: 10.1007/s00428-020-02881-x.</mixed-citation><mixed-citation xml:lang="en">Bosmuller H., Traxler S., Bitzer M. et al. (2020). The evolution of pulmonary pathology in fatal COVID-19 disease: an autopsy study with clinical correlation. Virchows Arch., 477 (3), 349-357. doi: 10.1007/s00428-020-02881-x.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Патологическая анатомия COVID-19: Атлас / O. В. Зайратьянц, М.В. Cамсонова, Л.М. Михалева и др. / под общ. ред. О.В. Зайратьянца. М.: ГБУ «НИИОЗММ ДЗМ», 2020. 140 с.</mixed-citation><mixed-citation xml:lang="en">Zairatiants O.V., Samsonova M.V., Mikhaleva L.M. et al. (2020). COVID-19 Pathological Anatomy: Atlas. Moscow, 140 p. In Russ.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Suess C., Hausmann R. Gross and histopathological pulmonary findings in a COVID-19 associated death during self-isolation // Int. J. Legal. Med. 2020. Vol. 134 (4). P. 1285-1290. doi: 10.1007/s00414-020-02319-8.</mixed-citation><mixed-citation xml:lang="en">Suess C., Hausmann R. (2020). Gross and histopatho-logical pulmonary findings in a COVID-19 associated death during self-isolation. Int. J. Legal. Med., 134 (4), 1285-1290. doi: 10.1007/s00414-020-02319-8.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Надеев А.П., Козяев М.А., Абышев А.А. и др. Внебольничная пневмония: эпидемиология, этиология и клинико-морфологические параллели // Journal of Siberian Medical Sciences. 2019. № 4. С. 20-29.</mixed-citation><mixed-citation xml:lang="en">Nadeev A.P., Kozyaev M.A., Abychev A.A. et al. (2019). Community-acquired pneumonia: epidemiology, etiology and clinical-morphological parallels. Journal of Siberian Medical Sciences, 4, 20-29.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Pomara C., Volti G., Cappello F. COVID-19 deaths: are we sure it is pneumonia? Please, autopsy, autopsy, autopsy! // J. Clin. Med. 2020. Vol. 9 (5). P. 1259. doi: 10.3390/jcm9051259.</mixed-citation><mixed-citation xml:lang="en">Pomara C., Volti G., Cappello F. (2020). COVID-19 deaths: are we sure it is pneumonia? Please, autopsy, autopsy, autopsy! J. Clin. Med., 9 (5), 1259. doi: 10.3390/jcm9051259.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
