Experience of using a copper vapor laser at a wavelength of 578 nm in the treatment of xanthelasma palpebrarum: a case report series
https://doi.org/10.31549/2542-1174-2024-8-4-7-20
Abstract
Introduction. Xanthelasma palpebrarum is a marked cosmetic defect and leads to reduced quality of life in patients. Non-selective technologies (for example, radiofrequency exposure and the use of ablative lasers) can lead to scarring, eyelash loss and severe functional disorders of the eye (including incomplete eyelid closure) because of insuffi cient skin thickness.
Aim . To evaluate the eff ectiveness of xanthelasma palpebrarum treatment with copper vapor laser radiation under dermatoscopy control.
Materials and methods. Treatment of grade I–IV xanthelasma palpebrarum was performed in 47 fairskinned women and men aged 28–72 years. The procedures were performed using a copper vapor laser at an average power of 0.6–0.8 W, wavelength 578 nm, exposure time 0.2 s, and spot diameter 1 mm. The maximum discoloring to gray of the xanthelasma surface was the criterion for laser pulse energy selection. The treatment was performed in one session under dermatoscopy control of treatment uniformity.
Results. Treatment with a copper vapor laser allowed complete removal of xanthelasma palpebrarum areas in all patients, including IV degree, without recurrence within 24 months after the treatment.
Conclusion. The use of copper vapor laser radiation at a wavelength of 578 nm provided excellent results for the xanthelasma palpebrarum treatment without side effects. The use of dermatoscopy improved the result of laser application and prevented treatment recurrences.
About the Authors
I. V. Ponomarev
Lebedev Physical Institute of the Russian Academy of Sciences
Russian Federation
Russian Federation
Igor V. Ponomarev – Cand. Sci. (Phys. and Math.), Senior Researcher
53, Leninsky prosp., Moscow, 119991
S. B. Topchiy
Lebedev Physical Institute of the Russian Academy of Sciences
Russian Federation
Russian Federation
Sergey B. Topchiy – Cand. Sci. (Phys. and Math.), Senior Researcher
Moscow
S. V. Klyuchareva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Russian Federation
Svetlana V. Klyuchareva – Dr. Sci. (Med.), Professor
St. Petersburg
P. G. Vlasov
Plastic Surgery and Laser Cosmetology “Perm Phlebocenter”
Russian Federation
Russian Federation
Pavel G. Vlasov – Cand. Sci. (Med.), Clinic of Phlebology
Perm
References
1. Al Aboud A.M., Shah S.S., Blair K., Al Aboud D.M. Xanthelasma palpebrarum. StatPearls. StatPearls Publishing, Treasure Island (FL), 2023. URL: https://europepmc.org/article/nbk/nbk531501 (accessed 24.06.2024).
2. Addison T. On a certain aff ection of the skinvitiligoidea-α plana, β tuberosa. Guy’s Hosp. Rep. 1851;7:265.
3. Lee H.Y., Jin U.S., Minn K.W., Park Y.O. Outcomes of surgical management of xanthelasma palpebrarum. Arch. Plast. Surg. 2013;40(4):380-386. DOI: 10.5999/aps.2013.40.4.380.
4. Khode S., Tan S.H.T., Tan E.A., Uppal S. Xanthelasma palpebrarum: more than meets the eye. Indian J. Otolaryngol. Head Neck Surg. 2019;71(1):439-446. DOI: 10.1007/s12070-018-1345-0.
5. Di M., Zhang Y., Zeng R. et al. The pro-angiogenesis eff ect of miR33a-5p/Ets-1/DKK1 signaling in ox-LDL induced HUVECs. Int. J. Biol. Sci. 2021;17(15):41224139. DOI: 10.7150/ijbs.60302.
6. Klyuchareva S.V., Ponomarev I.V. Application of a copper vapour laser for the treatment of skin xanthomatosis. Vestnik Dermatologii i Venerologii. 2007;4:52-54. (In Russ.)
7. Chopra K., Calva D., Sosin M. et al. A comprehensive examination of topographic thickness of skin in the human face. Aesthet Surg. J. 2015;35(8):1007-1013. DOI: 10.1093/asj/sjv079.
8. Cannon P.S., Ajit R., Leatherbarrow B. Effi cacy of trichloroacetic acid (95%) in the management of xanthelasma palpebrarum. Clin. Exp. Dermatol. 2010;35(8):845848. DOI: 10.1111/j.1365-2230.2010.03818.x.
9. Ritina I.F., Rubins S.A., Rubins A.Y. Experience of removing benign neoplasms of skin in cervicofacial area using the method of plasma ablation. Vestnik Dermatologii i Venerologii. 2017;93(4):44-52. (In Russ.)
10. Laftah Z., Al-Niaimi F. Xanthelasma: An update on treatment modalities. J. Cutan. Aesthet. Surg. 2018;11(1):1-6. DOI: 10.4103/jcas.jcas_56_17.
11. Abdelkader M., Alashry S.E. Argon laser versus erbium:YAG laser in the treatment of xanthelasma palpebrarum. Saudi J. Ophthalmol. 2015;29(2):116-120. DOI: 10.1016/j.sjopt.2014.09.017.
12. Karsai S., Czarnecka A., Raulin C. Treatment of xanthelasma palpebrarum using a pulsed dye laser: a prospective clinical trial in 38 cases. Dermatol. Surg. 2010;36(5):610-617. DOI: 10.1111/j.15244725.2010.01514.x.
13. Berger C., Kopera D. KTP laser coagulation for xanthelasma palpebrarum. J. Dtsch. Dermatol. Ges. 2005;3(10):775-779. DOI: 10.1111/j.16100387.2005.05746.x.
14. Jung S.Y., Hwang N.H., Yoon E.S., Park S.H. Erbium: yttrium aluminum garnet laser treatment for xanthelasma palpebrarum. Medical Lasers. 2017;6(1):24-28. DOI: 10.25289/ML.2017.6.1.24.
15. Karsai S., Schmitt L., Raulin C. Is Q-switched neodymium-doped yttrium aluminium garnet laser an eff ective approach to treat xanthelasma palpebrarum? Results from a clinical study of 76 cases. Dermatol. Surg. 2009;35(12):1962-1969. DOI: 10.1111/j.15244725.2009.01314.x.
16. Raulin C., Schoenermark M.P., Werner S., Greve B. Xanthelasma palpebrarum: treatment with the ultrapulsed CO2 laser // Lasers Surg. Med. 1999;24(2):122-127. DOI: 10.1002/(sici)1096-9101(1999)24:2<3C122::aidlsm7>3E3.0.co;2-6.
17. Park E.J., Youn S.H., Cho E.B. et al. Xanthelasma palpebrarum treatment with a 1,450-nm-diode laser // Dermatol. Surg. 2011;37(6):791-796. DOI: 10.1111/j.15244725.2011.01945..x.
18. Parver D.L., Dreher R.J., Kohanim S. et al. Ocular injury after laser hair reduction treatment to the eyebrow // Arch. Ophthalmol. 2012;130(10):1330-1334. DOI: 10.1001/archophthalmol.2012.1988.
19. Klyuchareva S.V., Ponomarev I.V., Pushkareva A.Е. Therapy of skin vascular malformations using copper vapor laser and pulsed dye laser. Vestnik Dermatologii i Venerologii. 2018;94(1):67-77. DOI: 10.25208/00424609-2018-94-1-67-77. (In Russ.)
20. Klyuchareva S.V., Ponomarev I.V., Topchiy S.B., Pushkareva A.Е. Treatment of rhinophyma using a copper vapor laser. Vestnik Dermatologii i Venerologii. 2018;94(5):50-58. DOI: 10.25208/0042-4609-2018-94-5-50-58. (In Russ.)
Review
For citations:
Ponomarev I.V., Topchiy S.B., Klyuchareva S.V., Vlasov P.G. Experience of using a copper vapor laser at a wavelength of 578 nm in the treatment of xanthelasma palpebrarum: a case report series. Journal of Siberian Medical Sciences. 2024;8(4):7-20. (In Russ.) https://doi.org/10.31549/2542-1174-2024-8-4-7-20
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