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INTENSITY OF VASCULAR INFLAMMATION AT PATIENTS WITH ARTERIAL HYPERTENSION AGAINST PERFORMED THERAPY

Abstract

The objective of research is to carry out comparative studying of levels of markers of vascular inflammation in blood serum at patients with arterial hypertension against hypotensive therapy. Materials and methods . 120 men (middle age was 33,4 ± 2,9 years) with verified diagnosis of arterial hypertension receiving standard anti-hypertensive therapy (losartan) are examined. The following data was defined in blood serum: concentration of glucose and fractions of cholesterol (TG, HDL, VLDL, LDL), endothelin-1, homocysteine and chCRP. Results . The more HC high levels and chCRP in blood serum at patients with unachieved AH level in comparison with group of patients at whom the AH level against hypotensive therapy reached target values are registered. Conclusion . The received results testify to associativity of intensity of vascular inflammation and efficiency of hypotensive therapy.

About the Authors

V. A. Elykomov
SBEI HPE «Altai State Medical University» of the Ministry of Health; RSBHE «Altai regional clinical hospital»
Russian Federation


G. I. Kostyuchenko
RSBHE «Altai regional clinical hospital»
Russian Federation


O. G. Viun
FRSHE «Medicosanitary hospital of the Ministry of Internal Affairs of Russia in Altai Krai»
Russian Federation


L. A. Kostyuchenko
SBEI HPE «Altai State Medical University» of the Ministry of Health
Russian Federation


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Review

For citations:


Elykomov V.A., Kostyuchenko G.I., Viun O.G., Kostyuchenko L.A. INTENSITY OF VASCULAR INFLAMMATION AT PATIENTS WITH ARTERIAL HYPERTENSION AGAINST PERFORMED THERAPY. Journal of Siberian Medical Sciences. 2015;(1):11.

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ISSN 2542-1174 (Print)