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RESULTS OF TREATMENT BY IMMUNOSUPRESSIVE MEDICINES AT CHILDREN WITH JUVENILE ARTHRITIS

Abstract

Purpose : an assessment of efficiency and safety of immunosuppressive therapy at children with the juvenile arthritis (JA). Methods : the comparative analysis of clinical data of laboratory on immunosuppressive therapy at 110 patients with JA. Results . Reliable depression of laboratory activity of a blood on MCT and GIBM is revealed. On GIBT the average level of CRP is 0,8 ± 0,2 mg/l, an ESR - 10,1 ± 1,2 mm/h, p < 0,05, it is lower, than at children with standard schemes of treatments. Frequency of occurrence of collateral reactions didn’t differ on MTH and GIBT. Conclusions: MCT remains the main preparation in treatment of JA. GIBM allow to achieve remission quickly.

About the Author

S. S. Pritchina
SBEI HPE «Kemerovo State Medical Academy» of Ministry of Health
Russian Federation


References

1. Revision of the Proposed Classification Criteria for Juvenile Idiopatic Arthritis. Durban, 1997 / R.E. Petty [et al.] // J. Rheumat. - 1998. - Vol. 25, N 10. - Р. 1991-94.

2. Beukelman T. American College of Rheumatology. Recommendations for the Treatment of Juvenile Idiopathic Arthritis : Initiation and Safety Monitoring of Therapeutic Agents for the Treatment of Arthritis and Systemic Features / Т. Beukelman // Arthritis Care Res. - 2011. - Vol. 63 (4). - Р. 465-482.

3. Алексеева Е. И. Ювенильный ревматоидный артрит : этиология, патогенез, клиника, алгоритмы диагностики и лечения : руководство для врачей / Е. И. Алексеева, П. Ф. Литвицкий. - М. : ВЕДИ, 2007. - 368 с.

4. Serum cytokines in juvenile rheumatoid arthritis : correlation with conventional inflammation parameters and clinical subtypes / Н. Mangge [et al.] // Arthr. Rheum. - 1995. - Vol. 38. - Р. 211-220.

5. Medication choices in juvenile rheumatoid arthritis / R. Mier [et al.] // J. Clin. Rheumatol. - 1996. - Vol. 2. - Р. 262-267.

6. International League of Associations for Rheumatology classification of juvenile idiopathic arthritis : second revision, Edmonton, 2001 / R. E. Petty [et al.] // J. Rheumatol. - 2004. - Vol. 31. - Р. 390-392.

7. Халафян А. А. Современные статистические методы медицинских исследований / А. А. Халафян. - М., 2014. - 320 с.

8. Алексеева Е. И. Ювенильный ревматоидный артрит : этиология, патогенез, клиника, алгоритм диагностики и лечения : руководство для врачей, преподавателей, научных сотрудников / Е. И. Алексеева, П. Ф. Литвицкий ; под общ. ред. А. А. Баранова. - М. : ВЕДИ, 2007. - 348 с.

9. Баранова А. А. Клинические рекомендации для педиатров. Детская ревматология (ювенильный артрит) / А. А. Баранова, Е. И. Алексеева ; под ред. А. А. Барановой ; Науч. центр здоровья детей РАМН. - М. : Педиатрь, 2013. - 120 с.


Review

For citations:


Pritchina S.S. RESULTS OF TREATMENT BY IMMUNOSUPRESSIVE MEDICINES AT CHILDREN WITH JUVENILE ARTHRITIS. Journal of Siberian Medical Sciences. 2015;(6):22.

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ISSN 2542-1174 (Print)