GENETICAL POLYMORPHISM OF ENDOTHELIAL DYSFUNCTION AND SYSTEMIC HEMOSTASIS AT PATIENTS WITH VIBRATION DISEASE COMBINED WITH ARTERIAL HYPERTENSION
Abstract
The characteristic of genetical polymorphism of endothelin-1 EDN1, NOS3(e) endothelial NO synthase, PAI1 activator of plasminogen of type 1, GP1ba of thrombocytic glycoprotein-1в and TGF-b gene, as early predictors of endothelium lesion and disease illness and arterial hypertension. It is shown that at patients with combined forms of pathobiology the genetical pathological polymorphic options which are responsible for state endothelial and hemostasiological processes with high frequency are revealed.
About the Authors
L. A. Shpagina
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»; SBHE NR «City clinical hospital № 2»
Russian Federation
Russian Federation
O. N. Gerasimenko
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
Z. K. Chachibaya
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
V. A. Drobyshev
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
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Review
For citations:
Shpagina L.A., Gerasimenko O.N., Chachibaya Z.K., Drobyshev V.A. GENETICAL POLYMORPHISM OF ENDOTHELIAL DYSFUNCTION AND SYSTEMIC HEMOSTASIS AT PATIENTS WITH VIBRATION DISEASE COMBINED WITH ARTERIAL HYPERTENSION. Journal of Siberian Medical Sciences. 2015;(1):35.
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