INVOLVEMENT OF GENETIC POLYMORPHISMS OF MATRIX METALLOPROTEINASES IN FORMATION OF ESSENTIAL HYPERTENSIA
Abstract
The essential hypertensia and its complications are a global problem of health care. The general prevalence of essential hypertensia at the 25 years-older population today exceeds 40 %. Research is devoted to new data on involvement of genetic polymorphisms of -1673 1G/2G MMP-1 (rs1799750) and -153 C/T MMP-7 (rs11568818) of matrix metalloproteinases in formation of essential hypertensia. It is shown that the of -153 TT MMP-7 (rs11568818) genotype is associated with higher levels of arterial pressure at patients with essential hypertensia.
About the Author
M. I. Moskalenko
FSAEI HE «Belgorod State National Research University»
Russian Federation
Russian Federation
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Review
For citations:
Moskalenko M.I. INVOLVEMENT OF GENETIC POLYMORPHISMS OF MATRIX METALLOPROTEINASES IN FORMATION OF ESSENTIAL HYPERTENSIA. Journal of Siberian Medical Sciences. 2016;(3):9.
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