The level of Ddimer in patients with basal cell skin cancer in the immediate and remote postoperative period

Abstract

The level of Ddimer in the blood was determined in 36 patients with basal cell skin cancer. The analysis was made before the surgical treatment, on the first postoperative day, on the third, fifth, seventh, and tenth postoperative days, and in 18 months after the operation. For comparison, the blood Ddimer level was determined in 17 relatively healthy volunteers of the same age and sex (comparison group 1), and in 20 patients operated on for skin fibroma (comparison group 2) of the same age and sex as the patients in the main group. In patients with basal cell skin cancer the blood Ddimer level was elevated before the start of surgical treatment. On the first postoperative day the level increased sharply, then it gradually decreased, but did not restored to normative values, and it was elevated both in the immediate and in the remote postoperative period. The absence of a return to the normal level of Ddimer in the blood in the immediate and remote postoperative periods in patients with basal cell skin cancer indicates disturbances of rheological blood properties in this category of patients.