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Community-acquired pneumonia: epidemiology, etiology and clinical-morphological parallels

https://doi.org/10.31549/2542-1174-2019-4-20-29

Abstract

Retrospective assessment of results of pathoanatomical researches on the deceased patients with community-acquired pneumonia treated in City Clinical Hospital No. 1 (Novosibirsk) in 2016–2018 is carried out for the purpose of studying gender, age features, etiology, clinical-morphological forms of the community-acquired pneumonia which resulted in lethal outcome. Morphological and bacteriological researches of lung samples in deceased patients with the diagnosis of pneumonia were conducted.

It is revealed that lethal outcomes owing to community-acquired pneumonia were more often observed in men, than in women, at advanced and senile age (56–67%). The rate of lethal outcomes owing to community-acquired pneumonia among all number of pathoanatomical thanatopsy made 2.6–3.8%. Lethality within the period of 24 hours of hospitalization was registered in 15–32% of cases. The divergence of clinical and pathoanatomical diagnoses reached 17.6%. Klebsiella pneumoniaе, Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa and also mixed-strain infection were the most widespread verifi ed causative agents of community-acquired pneumonia. The main clinical-morphological form of community-acquired pneumonia was the widespread bronchial pneumonia (purulent, with abscessing) (up to 87.8%) which did not present specifi c morphological picture depending on a type of the causative agent.

Conflict of interest. The authors declare no conflict of interest.

About the Authors

A. P. Nadeev
Novosibirsk State Medical University; Novosibirsk City Clinical Hospital No. 2
Russian Federation

Nadeev Aleksandr Petrovich — Dr. Sci. (Med.), Professor, Head of the Pathological Anatomy Department

Pathologist



M. A. Kozyaev
Novosibirsk State Medical University; Novosibirsk City Clinical Hospital No. 2
Russian Federation

Kozyaev Mikhail Aleksandrovich — Cand. Sci. (Med.), Assistant Professor of the Pathological Anatomy Department

Head of the Pathology Department,



A. A. Abyshev
Novosibirsk State Medical University
Russian Federation
Abyshev Aleksandr Andreyevich — Post-graduate Student of the Pathological Anatomy Department


M. N. Chekanov
Novosibirsk State Medical University
Russian Federation
Chekanov Mikhail Nikolayevich — Dr. Sci. (Med.), Professor of the General Surgery Department


E. M. Blagitko
Novosibirsk State Medical University
Russian Federation
Blagitko Evgeny Mikhaylovich — Dr. Sci. (Med.), Professor of the Hospital and Pediatric Surgery Department


I. V. Peshkova
Novosibirsk State Medical University
Russian Federation
Peshkova Inessa Viktorovna — Dr. Sci. (Med.), Assistant Professor of the Anesthesiology and Critical Care Medicine n.a. Professor I.P. Vereshchagin Department


E. V. Ovsyanko
Novosibirsk State Medical University
Russian Federation
Ovsyanko Elena Vladimirovna — Dr. Sci. (Med.), Professor of the Human Anatomy Department


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Review

For citations:


Nadeev A.P., Kozyaev M.A., Abyshev A.A., Chekanov M.N., Blagitko E.M., Peshkova I.V., Ovsyanko E.V. Community-acquired pneumonia: epidemiology, etiology and clinical-morphological parallels. Journal of Siberian Medical Sciences. 2019;(4):20-29. https://doi.org/10.31549/2542-1174-2019-4-20-29

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ISSN 2542-1174 (Print)