Possible risk factors and predictors of pneumonia development in pertussis infection
https://doi.org/10.31549/2542-1174-2019-4-109-119
Abstract
The open single center retrospective study of 418 case histories of children who were observed with pertussis infection in Novosibirsk Children’s City Clinical Hospital No. 3 was conducted. The objective of the research was to study characteristics of the course of pertussis infection complicated by pneumonia and to identify probable risk factors, as well as clinical laboratory predictors, ways of prevention of the pertussis complicated by pneumonia.
The analysis of the received results showed that absence of vaccination, the burdened comorbid background and the artificial feeding being the probable risk factors of the complicated pertussis, moreover, the combination of the above mentioned factors results in the high frequency of development of pertussis-associated pneumonia. The significant increase in frequency of cough, the rise in leukocytosis, neutrocytosis in the course of pertussis should be considered as predictors of the developing pneumonia. Vaccination is an adequate method of prevention of the pertussis infection complicated by pneumonia.
Conflict of interest. The authors declare no conflict of interest.
About the Authors
A. V. Vasyunin
Novosibirsk State Medical University
Russian Federation
Vasyunin Aleksandr Vasilyevich — Dr. Sci. (Med.), Professor of the Infectious Diseases Department
Russian Federation
Vasyunin Aleksandr Vasilyevich — Dr. Sci. (Med.), Professor of the Infectious Diseases Department
E. I. Krasnova
Novosibirsk State Medical University
Russian Federation
Krasnova Elena Igorevna — Dr. Sci. (Med.), Professor, Head of the Infectious Diseases Department,
Russian Federation
Krasnova Elena Igorevna — Dr. Sci. (Med.), Professor, Head of the Infectious Diseases Department,
G. S. Karpovich
Novosibirsk State Medical University
Russian Federation
Russian Federation
Karpovich Gleb Sergeyevich — Teaching Assistant of the Infectious Diseases Department
52, Krasny Prospect, Novosibirsk, 630091
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For citations:
Vasyunin A.V., Krasnova E.I., Karpovich G.S. Possible risk factors and predictors of pneumonia development in pertussis infection. Journal of Siberian Medical Sciences. 2019;(4):109-119. https://doi.org/10.31549/2542-1174-2019-4-109-119
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