Genetic predisposition to the formation of acne scars
https://doi.org/10.31549/2542-1174-2020-2-98-110
Abstract
The paper presents a literature review on the associations of molecular genetic markers with scar formation in patients with acne. Given the high prevalence of the disease and long-term negative aesthetic consequences, the problem of post-acne is very relevant. However, the detection of reliable prognostic markers of an increased risk of scar formation due to acne is remaining an unsolved problem. The paper reviews most recent publications devoted to the analysis of molecular genetic markers with post-acne scars and concluded that the study of the genetic aspects of scar formation in patients with acne is almost at the initial stage. The lack of effective means for the prevention and treatment of acne scars necessitates a further search.
About the Authors
O. B. Nemchaninova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head, Department of Dermatovenereology and Cosmetology,
Novosibirsk
E. V. Chernikova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Cand. Sci. (Med.), Assistant, Department of Dermatovenereology and Cosmetology,
52, Krasny Prospect, Novosibirsk, 630091
Yu. V. Maksimova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Head, Department of Medical Genetics and Biology,
Novosibirsk
T. B. Reshetnikova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Dr. Sci. (Med.), Professor, Department of Dermatovenereology and Cosmetology,
Novosibirsk
A. V. Spitsyna
Novosibirsk State Medical University
Russian Federation
Russian Federation
Cand. Sci. (Med.), Associate Professor, Department of Dermatovenereology and Cosmetology,
Novosibirsk
V. N. Maksimov
Novosibirsk State Medical University;
Research Institute of Internal and Preventive Medicine (Novosibirsk)
Dr. Sci. (Med.), Professor, Head, Laboratory of Molecular Genetic Research of Therapeutic Diseases,
Novosibirsk
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Review
For citations:
Nemchaninova O.B., Chernikova E.V., Maksimova Yu.V., Reshetnikova T.B., Spitsyna A.V., Maksimov V.N. Genetic predisposition to the formation of acne scars. Journal of Siberian Medical Sciences. 2020;(2):98-110. (In Russ.) https://doi.org/10.31549/2542-1174-2020-2-98-110
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