ANALYSIS OF COMPLEX CHROMOSOMAL DISTURBANCES IN GROUP OF PATIENTS WITH ACUTE LEUKOSIS
Abstract
Research of significant genetic aberrations in group of oncohematological patients in Novosibirsk by analysis method on DNA microchips and assessment of their role in the prognosis for a disease is conducted. The obtained data are compared with efficiency of polychemotherapy and prognostic groups are created. In group of the adverse prognosis the multiple genetic aberrations took place more often, unlike the group of patients with the favorable forecast of disease at who had mainly single genetic aberrations. Implanting of genetic chips allows to reveal wide range of genetic anomalies for single-step definition of the forecast of patients with acute leukosis.
About the Authors
R. V. Tarnovskiy
SBEI HPE «Novosibirsk State Medical University» of Ministry of Health
Russian Federation
Russian Federation
T. I. Pospelova
SBEI HPE «Novosibirsk State Medical University» of Ministry of Health
Russian Federation
Russian Federation
M. A. Zenkova
FSBHE «Institute of chemical biology and fundamental medicine of the SB RAS»
Russian Federation
Russian Federation
S. A. Tairova
SBHE NR «City clinical hospital № 2»
Russian Federation
Russian Federation
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Review
For citations:
Tarnovskiy R.V., Pospelova T.I., Zenkova M.A., Tairova S.A. ANALYSIS OF COMPLEX CHROMOSOMAL DISTURBANCES IN GROUP OF PATIENTS WITH ACUTE LEUKOSIS. Journal of Siberian Medical Sciences. 2015;(3):55.
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