INFLUENCE OF HORMONAL CONTRACEPTION AT WOMEN ON THE COURSE OF AUTOIMMUNE THYROIDITIS
Abstract
The objective of research is to study and estimate influence of hormonal contraceptives on function of thyroid gland by means of definition of the content of thyritropic hormone (TTH) and free thyroxine (T4fr.), antibodies to thyroid peroxidase in blood serum at patients with autoimmune thyroiditis. Research included 40 women. 20 of them had autoimmune thyroiditis and were included into the main group, 20 healthy women made the group of control. As a result of assessment of dynamics of laboratory indicators it is revealed that hormonal contraceptives have no negative impact on TTG and T4fr content in blood serum, thus they have immunosuppressive effect on levels of antibodies to thyroid peroxidase that can be a favorable factor for course of autoimmune thyroiditis. Decrease of L-thyroxine dose against reception of hormonal contraceptives is possible after consultation with the endocrinologist.
About the Authors
I. O. Marinkin
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
T. M. Sokolova
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
K. Y. Makarov
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
A. V. Usova
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
E. A. Dubkova
SBEI HPE «Novosibirsk State Medical University of Ministry of Health»
Russian Federation
Russian Federation
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Review
For citations:
Marinkin I.O., Sokolova T.M., Makarov K.Y., Usova A.V., Dubkova E.A. INFLUENCE OF HORMONAL CONTRACEPTION AT WOMEN ON THE COURSE OF AUTOIMMUNE THYROIDITIS. Journal of Siberian Medical Sciences. 2015;(3):56.
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