ASSESSMENT OF INTENSITY OF CYTOKINE REACTIONS OF FIBROSIS AT COMORBIDE PATIENTS WITH COPD

Abstract

The objective of research : to compare interleukin-8 (IL-8) levels of blood plasma and molecule of intercellular adhesion-1 (ICAM-1) as biomarkers of progressing massive fibrosis at 38 patients. Materials and methods . Plasma of patients was measured on the maintenance of intercellular molecule of adhesion-1 and IL-8. Results . High levels in IL-8 and ICAM-1 serum are important as these results can indicate attractants of neutrophils and molecules of adhesion that are connected to a medium-weight chronic obstructive pulmonary disease with accompanying coronary heart disease, and hidden processes of the progressing massive fibrosis.