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Assessment of efficiency and the safety of Ovariamin® drug in normalization of menstrual cycle

Abstract

We performed an open controlled trial of efficiency and the safety of Ovariamin® drug in treatment of menstrual disorders. The research included 33 patients with menstrual disorder which were divided into 2 groups: the 1st group - menstrual disorders /ICD10/N91. The absent scanty and infrequent menstruation (n = 17); the 2nd group - menstrual disorders /ICD10/ N92. Abundant, frequent and irregular menstruations (n = 16). The analysis of clinical efficiency of administration of Ovariamin® drug in 3 months showed the following: normalization of menstrual cycle in the 1st group was registered in 52.9% of patients, in the 2nd group - in 62.5%; decrease of menstrual pain was registered in 52.9% in the 1st group and in 62.5% in the 2nd group. Satisfaction of patients in the end of the therapy was revealed in 88.2% in the 1st group, and in 93.8% in the 2nd group respectively; efficiency in maintenance of regular menstrual cycle in the next 6 months after treatment was revealed in 76.5% of patients of the 1st group, and in 75% of the 2nd group of patients.

About the Authors

T. M. Sokolova
Novosibirsk State Medical University
Russian Federation


I. O. Marinkin
Novosibirsk State Medical University
Russian Federation


T. V. Kiseleva
Novosibirsk State Medical University
Russian Federation


V. M. Kuleshov
Novosibirsk State Medical University
Russian Federation


K. Ju. Makarov
Novosibirsk State Medical University
Russian Federation


Z. B. Khayatova
Novosibirsk State Medical University
Russian Federation


A. V. Jakimova
Novosibirsk State Medical University
Russian Federation


A. V. Usova
Novosibirsk State Medical University
Russian Federation


References

1. Ginekologija. Nacional’noeRukovodstvo (2009). Moscow: GjeotarMedia.

2. Ovariamin® Prescribing Information (consumer information).

3. Kuznecova I.V., Sheveleva T.V. (2013). The effectiveness of vitaminvegetative complex in the treatment of menstrual disorder in young women. Gynecology, 2, 12-19.

4. Matteson K.A., Raker C.A., Clark M.A., Frick K.D. (2013). Abnormal uterine bleeding, health status, and usual source of medical care: analyses using the Medical Expenditures Panel Survey. J Womens Health (Larchmt), 22, 959-965.

5. World Medical Association (WMA). WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. (2013). Retrieved Jule 3, 2015 from http://www.wma.net/en/30publications/10policies/b3/index.html.pdf?printmediatype&footerright¼[page]/[toPage].

6. The order of the Ministry of Health of the RF “On approval of Rules of clinical practice in the Russian Federation” of June 19, 2003 No. 266 (Dokipediya: The order of the Ministry of Health of the RF “On approval of Rules of clinical practice in the Russian Federation” of June 19, 2003 N 266”).


Review

For citations:


Sokolova T.M., Marinkin I.O., Kiseleva T.V., Kuleshov V.M., Makarov K.J., Khayatova Z.B., Jakimova A.V., Usova A.V. Assessment of efficiency and the safety of Ovariamin® drug in normalization of menstrual cycle. Journal of Siberian Medical Sciences. 2017;(2):10-13.

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ISSN 2542-1174 (Print)