Clinical assessment of the severity of chronic cystitis in women of different age groups

The aim of the study was to estimate course the peculiarities of chronic cystitis in women of different ages. The study included 334 women with chronic cystitis (CC). The patients were divided into 3 age groups: group 1 — 20 to 39 years old; group 2 — 40 to 59 years old; group 3 — elderly age (60 years old and older). Cystoscopy was performed, the frequency of cystitis exacerbations was estimated, a survey was carried out using the PUF Scale (Pelvic Pain and Urgency/Frequency Patient Symptom Scale) questionnaire, and urination diaries were evaluated. A higher severity of symptoms was revealed in patients with leukoplakia in all age groups. However, the incidence of leukoplakia signifi cantly decreased with age. In this regard, the observed age-related increase in clinical symptoms of CC is most likely associated with the emergence of age-related pathogenesis factors. An inverse correlation between the presence of leukoplakia and mucosal edema was detected in women with the same symptoms. The two-way analysis of variance revealed two factors associated with increasing severity of chronic cystitis symptoms: age and the presence of squamous metaplasia (leukoplakia). 

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