The functional state of the left atrium in individuals exposed to organic solvents
Abstract
In order to study the functional state of the left atrium in individuals exposed to organic solvents of the aromatic series, 80 women working at an industrial enterprise in the profession of a painter and contacting with paints of various names on the basis of organic solvents of the aromatic series were examined, the main of which were: toluene, xylene, acetone, butyl acetate, ethyl acetate, butanol, which were intensively released into the air of the working area during the painting works. The control group was represented by healthy women — 20 people, an average age 39.3 ± 4.1 years; comparison group was represented by the individuals with vegetative-dishormonal cardiomyopathy (VDC) — 30 people, an average age 40.5 ± 3.4 years, who had no contact with toxic substances and patients with mild iron deficiency anemia (IDA) — 25 people, an average age 39.68 ± 3.3 years. All individuals underwent echocardiography.
It was revealed that depending on the length of service, there is a change in the activity of the left atrium, which is expressed in the formation of the mechanism of regulation of the left ventricular myocardial function by the сontracting atrium. This atrial mechanism begins to form in the groups of medium- and high-level painters with VDC. Hyperfunctional mode of the left atrium is noted in painters with anemic cardiomyopathy. In general, the state of the contractile function of the left heart in painters with secondary cardiomyopathy reflects the complex mechanism of interaction between the ventricle and the atrium, which occurs with the activation of their compensatory and adaptive resources, aimed at maintaining the heart function at the optimal level for the body in conditions of prolonged exposure to damaging factors.
About the Authors
S. V. Tretyakov
Novosibirsk State Medical University
Russian Federation
Russian Federation
Tretyakov Sergey Vladislavovich — Dr. Sci. (Med.), Professor of the Department of Polyclinic Therapy and General Medical Practice (Family Medicine).
52, Krasny Prospect, Novosibirsk, 630091
A. A. Popova
Novosibirsk State Medical University
Russian Federation
Russian Federation
Popova Anna Aleksandrovna — Dr. Sci. (Med.), Associate Professor, Head of the Department of Polyclinic Therapy and General Medical Practice (Family Medicine)
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Review
For citations:
Tretyakov S.V., Popova A.A. The functional state of the left atrium in individuals exposed to organic solvents. Journal of Siberian Medical Sciences. 2019;(3):84-94.
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