Uv spectrophotometric determination of bis-[3’(3,5-di-tret-butyl4-hydroxyphenyl)propyl]sulfide and dodecyl(3,5-dimethyl-4hydroxybenzyl)sulfide

Abstract

Bis-[3’(5-di-tret-butyl-4-hydroxyphenyl)propyl]sulfide and dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide are new phenolic sulfur-containing antioxidants. The purpose of this study is to develop spectrophotometric techniques for establishing the authenticity and quantification of these substances. During the validation of the procedure, calibration graphs were constructed to assess linearity at concentrations ranging from 0.001 to 0.01% for bis [3’(3,5-di-tret-butyl4-hydroxyphenyl)propyl]sulfide and from 0.0005 to 0.005% for dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide. The correlation coefficient for bis-[3’(3,5-di-tret-butyl-4-hydroxyphenyl)propyl]sulfide was 0.999, for dodecyl(3,5-dimethyl4-hydroxybenzyl)sulfide — 0.996; the detection limit calculated using the calibration graph data was 3.14 · 10 –5 and 3.75 · 10 –5 %, the limit of quantification was 0.00103 and 0.00108% for bis-[3’(3,5-di-tret-butyl-4-hydroxyphenyl)propyl] sulfide and dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide respectively. The value of relative standard deviation (RSD) in assessing the precision of both methods did not exceed the permissible 2%.
Thus, the developed methods can be used to establish the authenticity and for the quantification of bis-[3’(5-di-tretbutyl-4-hydroxyphenyl)propyl]sulfide and dodecyl(3,5-dimethyl-4-hydroxybenzyl)sulfide.