Structural and functional state of the heart in elderly patients with combined broncho-obstructive pathology and arterial hypertension
https://doi.org/10.31549/2542-1174-2020-1-55-64
Abstract
In order to specify features of a structural and functional state of the heart in the combination of chronic obstructive pulmonary disease (COPD) and bronchial asthma (BA) in elderly people with arterial hypertension (AH) this research was conducted. The 15 men with COPD and BA (average age — 68.4 ± 3.6 years) were surveyed. The group of comparison consisted of 15 patients with COPD (average age — 63.4 ± 3.2 years). All patients had type B COPD.
It was revealed that in the combined broncho-obstructive pathology, unlike patients with COPD, the elderly people with AH show a greater degree of concentric hypertrophy of left ventricle with an increase in its contractility (namely, global longitudinal systolic capacity) against the background of lack of differences in its diastolic function and longitudinal in particular. When COPD and BA are combined the elderly people with AH, unlike patients with COPD, have a larger degree of impaired active relaxation of the right ventricle with an increase in its function, particularly global longitudinal systolic function, against the background of more pronounced pulmonary hypertension. The revealed features of hemodynamics of pulmonary circulation and function of right ventricle are the basis for choosing pathogenetically justified therapy aimed not only at decreasing the pulmonary artery pressure, but also at improvement of calcium mechanisms in both systole and diastole.
About the Authors
S. V. Tretyakov
Novosibirsk State Medical University
Russian Federation
Russian Federation
Tretyakov Sergey Vladislavovich — Dr. Sci. (Med.), Professor, Department of Polyclinic Therapy and General Medical Practice
52, Krasny Prospect, Novosibirsk, 630091
A. A. Popova
Novosibirsk State Medical University
Russian Federation
Popova Anna Aleksandrovna — Dr. Sci. (Med.), Assistant Professor, Head, Department of Polyclinic Therapy and General Medical Practice
Russian Federation
Popova Anna Aleksandrovna — Dr. Sci. (Med.), Assistant Professor, Head, Department of Polyclinic Therapy and General Medical Practice
A. A. Demin
Novosibirsk State Medical University
Russian Federation
Demin Aleksandr Aristarkhovich — Dr. Sci. (Med.), Professor, Head, Department of Hospital Therapy
Russian Federation
Demin Aleksandr Aristarkhovich — Dr. Sci. (Med.), Professor, Head, Department of Hospital Therapy
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Review
For citations:
Tretyakov S.V., Popova A.A., Demin A.A. Structural and functional state of the heart in elderly patients with combined broncho-obstructive pathology and arterial hypertension. Journal of Siberian Medical Sciences. 2020;(1):55-64. https://doi.org/10.31549/2542-1174-2020-1-55-64
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