Assessment of quality of life in patients with hypertension comorbid with chronic cerebrovascular diseases
Abstract
The study on assessing the quality of life of patients with arterial hypertension (AH) comorbid with chronic cerebrovascular diseases (CVD) involved 70 people of both sexes, aged 20 to 75 years, who underwent a comprehensive examination and treatment at the Clinic of the Federal Research Center of Fundamental and Translational Medicine (Novosibirsk). The study participants were divided into 3 groups: the main group included 23 patients with hypertension combined with chronic cerebrovascular diseases; the comparison group — 23 patients with isolated arterial hypertension (AH), and the control group — 24 patients with dorsopathies without cardiovascular pathology. Health-related quality of life (QOL) was assessed using the validated MOS SF-36 Questionnaire. Patients of the main group and the group of comparison underwent a course of drug therapy, in accordance with modern medical and economic standards.
The comparative analysis showed a significant decrease (by 21.8%) in the level of physical functioning, as well as in the mental component of health (by 20.49%) in patients with AH combined with chronic CVD, compared to patients with isolated AH. In comparison with the control group, there was a significant decrease in the main indices of QOL in patients with AH comorbid with chronic CVD. The course of inpatient therapy led to a significant increase in physical and role functioning, as well as significant increase in an integral indicator of QOL in patients of the main group — by 22.9%.
About the Authors
E. V. Sevost’yanova
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
Sevost’yanova Evgeniya Viktorovna — Cand. Sci. (Med.), Senior Researcher, Laboratory of the Pathogenesis of Somatic Diseases.
2, Timakova str., Novosibirsk, 630017
Yu. A. Nikolaev
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
Nikolaev Yurij Alekseevich — Dr. Sci. (Med.), Chief Scientific Researcher, Acting Deputy Director for Scientific and Medical Work, Head, Laboratory of Pathogenesis of Somatic Diseases.
Novosibirsk
V. Ya. Polyakov
Federal Research Center of Fundamental and Translational Medicine
Russian Federation
Russian Federation
Polyakov Vladimir Yakovlevich — Dr. Sci. (Med.), Leading Researcher, Laboratory of Pathogenesis of Somatic Diseases.
Novosibirsk
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Sevost’yanova E.V., Nikolaev Yu.A., Polyakov V.Ya. Assessment of quality of life in patients with hypertension comorbid with chronic cerebrovascular diseases. Journal of Siberian Medical Sciences. 2020;(4):52-62.
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