Use of cephalosporins in a multifield hospital of the Republic of Tajikistan
Abstract
Aim. Analysis of the use of cephalosporin antibiotics in a multifield hospital (MH) of the Republic of Tajikistan in 2011-2018.
Materials and methods. To assess the dynamics of the use of cephalosporins, the ATC/DDD methodology was used (parameters: index DDDs (Defined Daily Doses) / 100 bed-days, total DDDs per year, percentage of total DDDs).
Results. In the treatment of various infectious diseases, cephalosporins are much more often used in comparison with antimicrobial drugs (AMD) of other classes. The proportion of cephalosporins in the structure of all AMD used in the MH is about 70%. The undisputed leader is ceftriaxone, the use of which has increased by 7.5 times over the indicated period. The decline in the use of first-generation cephalosporins should be considered a positive trend in approaches to antibiotic therapy. There were only isolated cases of the use of 3rd generation cephalosporins — ceftazidime and cefoperazone, as well as the 4th generation cephalosporins — cefepime, which were random.
Conclusion. The results of the study can serve as a rationale for planning the procurement of drugs for multifield hospitals, as well as for the analysis of the antimicrobial drugs use rationality, taking into account the risk of antibiotic resistance development.
About the Authors
L. V. Savchenkova
Bogomolets National Medical University
Ukraine
Ukraine
Savchenkova Larisa Vasilyevna — Dr. Sci. (Med.), Professor, Department of Pharmacology
M. N. Saidova
Tajik National University
Tajikistan
Tajikistan
Saidova Mukhabbat Narzulloyevna — Cand. Sci. (Pharmaceut.), Head, Department of Pharmacy.
17, Rudaki Prospect, Dushanbe, 734025
I. P. Pulotzoda
Main Department of the State Surveillance Service of Healthcare and Social Protection in the Sughd Region
Tajikistan
Tajikistan
Pulotzoda Ilkhom Pulot — Head, Main Department of the State Surveillance Service for Health Care and Social Protection in the Sughd Region
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Review
For citations:
Savchenkova L.V., Saidova M.N., Pulotzoda I.P. Use of cephalosporins in a multifield hospital of the Republic of Tajikistan. Journal of Siberian Medical Sciences. 2020;(4):82-89.
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