Clinical, metabolic and hormonal features of the formation of impaired hypoglycemia awareness
https://doi.org/10.31549/2542-1174-2021-4-97-107
Abstract
The review presents the prevalence, pathogenetic aspects of the development of impaired hypoglycemia awareness in diabetes mellitus and its effect on the course of the disease. A key aspect in the pathogenesis of atypical hypoglycemias is the brain adaptation to a low glucose concentration in blood, which entails a disorder of hormonal response to hypoglycemia. This process is an autonomous dysfunction associated with hypoglycemia. It is noted the role of atypical hypoglycemia in the development of cardiovascular complications, cognitive impairments and pregnancy failure in patients with diabetes mellitus.
About the Authors
I. А. Reva
Novosibirsk State Medical University
Russian Federation
Russian Federation
Inna A. Reva — Clinical Resident, Department of Endocrinology
52, Krasny Prospect, Novosibirsk, 630091
I. А. Bondar
Novosibirsk State Medical University
Russian Federation
Russian Federation
Irina A. Bondar — Dr. Sci. (Med.), Professor, Head, Department of Endocrinology; Chief Endocrinologist, Siberian Federal District
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Review
For citations:
Reva I.А., Bondar I.А. Clinical, metabolic and hormonal features of the formation of impaired hypoglycemia awareness. Journal of Siberian Medical Sciences. 2021;(4):97-107. https://doi.org/10.31549/2542-1174-2021-4-97-107
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