ОБЗОР СВОЙСТВ И МЕТОДОВ ИССЛЕДОВАНИЯ МИТОХОНДРИАЛЬНОЙ ДНК
Аннотация
Благодаря уникальным свойствам мтДНК ее анализ широко применяется в диагностике митохондриальных заболеваний и судебно-медицинской экспертизе, изучении эволюции человека и генеалогических исследованиях, поиске причин старения, онкологических и социально-значимых соматических заболеваний. Исследования митохондриального генома требуют определенных технических и концептуальных знаний. В данном обзоре обобщенны сведения о свойствах, видах изменчивости, методах исследования и особенностях работы с мтДНК.
Об авторах
Е. Н. Воропаева
ФГБНУ «Научно-исследовательский институт терапии и профилактической медицины»
Россия
Россия
В. Н. Максимов
ФГБНУ «Научно-исследовательский институт терапии и профилактической медицины»; ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России
Россия
Россия
С. К. Малютина
ФГБНУ «Научно-исследовательский институт терапии и профилактической медицины»; ФГБОУ ВО «Новосибирский государственный медицинский университет» Минздрава России
Россия
Россия
M. Bobak
University College (London)
Россия
Россия
М. И. Воевода
ФГБНУ «Научно-исследовательский институт терапии и профилактической медицины»
Россия
Россия
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Рецензия
Для цитирования:
Воропаева Е.Н., Максимов В.Н., Малютина С.К., Bobak M., Воевода М.И. ОБЗОР СВОЙСТВ И МЕТОДОВ ИССЛЕДОВАНИЯ МИТОХОНДРИАЛЬНОЙ ДНК. Journal of Siberian Medical Sciences. 2016;(3):8.
For citation:
Voropayeva E.N., Maksimov V.N., Malyutina S.K., Bobak M., Voevoda M.I. REVIEW ON PROPERTIES AND METHODS OF MITOCHONDRIAL DNA RESEARCH. Journal of Siberian Medical Sciences. 2016;(3):8.
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