Markers of thrombophilia and endothelial dysfunction under the technogenic influence of the dust factor
Аннотация
Thrombophilia markers (rising of activity of the VIII coagulation factor, decrease of the activity of protein C) and endothelial dysfunction (rising of activity of von Willebrand factor, contents of glycosaminoglycans in blood, and microalbuminuria) are revealed at the prolonged technogenic impact of the dust factor in workers of the dust hazardous jobs. The revealed markers of thrombophilia and endothelial dysfunction correlate with degree of fibrogenity of dust aerosols in the workers contacting with highly fibrogenic and mild fibrogenic dust aerosols.
Об авторах
E. Cikalenko
Novosibirsk State Medical University; City Clinical Hospital No. 1
Россия
Россия
O. Dorn
Novosibirsk State Medical University; City Clinical Hospital No. 1
Россия
Россия
S. Peskov
Novosibirsk State Medical University; City Clinical Hospital No. 1
Россия
Россия
E. Stepanova
Novosibirsk State Medical University
Россия
Россия
M. Palamarchuk
Novosibirsk State Medical University
Россия
Россия
L. Vohminceva
Novosibirsk State Medical University
Россия
Россия
Список литературы
1. Barkagan Z.S. (2000). Uchenie o trombofilijah na sovremennom etape. Consilium, 6, 61-65.
2. Brodskaya Т.A., Nevzorova V.A., Geltser B.I., Motkina E.V. (2007). Endothelial dysfunction and respiratory diseases. Terapevticheskiy Arkhiv (Therapeutic Archive), 3, 76-84.
3. Velichkovskiy B.T. (1980). Fibrogennye pyli: osobennosti stroenija i mehanizma biologicheskogo dejstvija. Gorky: VolgoVyatskoe knizhnoe izdatelstvo. 88, 112-122.
4. Kim L.B., Zhilyakov I.V., Nikonova I.K. (2009). Serum levels of glycosaminoglycans, oxyproline, and fibronectin in patients with osteochondrosis of the vertebral column. Klinicheskaya Laboratornaya Diagnostika, 8, 16-19.
5. Papajan L.P. (2000). Problemy diagnostiki trombofilii. In: Problemy fiziologii i patologii gemostaza. (pp. 213-220). Barnaul.
Рецензия
Для цитирования:
, , , , , . Journal of Siberian Medical Sciences. 2017;(2):3-5.
For citation:
Cikalenko E.A., Dorn O.J., Peskov S.A., Stepanova E.G., Palamarchuk M.V., Vohminceva L.V. Markers of thrombophilia and endothelial dysfunction under the technogenic influence of the dust factor. Journal of Siberian Medical Sciences. 2017;(2):3-5.
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