ATYPICAL GEE’S DISEASE AT CHILDREN: LABORATORY AND TOOL FEATURES
Abstract
254 children aged from 2 till 14 years with signs of atypical coeliac disease took part in research. Serological markers of coeliac disease were revealed at 1/3 patients, thus antibodies to fabric transglutaminase were registered much less often - at 20,5 %, than to gliadine - at 79,5 % of number of serological positive patients. Antibodies were registered insignificantly more often at patients with acetonemic states (40,0 % of number surveyed) in the analysis of distribution the serological markers of coeliac disease among five studied groups, and it was reliable less often - only in group of patients with growth inhibition (5,6 % of number surveyed). Prognostic influence of type of the studied markers, their combination and level of rising on results of morphometric research wasn’t established.
About the Authors
A. N. Danilov
RSBHE «Children municipal hospital N 1» (Barnaul)
Russian Federation
Russian Federation
D. A. Danilov
RSBHE «Children municipal hospital N 1» (Barnaul)
Russian Federation
Russian Federation
D. Y. Latyshev
SBEI HPE «Altai state medical university» of the Russian Ministry of Health
Russian Federation
Russian Federation
Y. F. Lobanov
SBEI HPE «Altai state medical university» of the Russian Ministry of Health
Russian Federation
Russian Federation
K. G. Pechkina
RSBHE «Children municipal hospital N 1» (Barnaul)
Russian Federation
Russian Federation
References
1. Бельмер С. В. Проект рабочего протокола диагностики и лечения целиакии у детей / С. В. Бельмер // Вопр. дет. диетологии. - 2004. - Т. 2, № 1. - С. 87-103.
2. Ревнова М. О. Целиакия : учебно-методическое пособие для врачей и студентов медицинских факультетов / М. О. Ревнова. - СПб. : Санкт-Петербургская государственная педиатрическая медицинская академия, 2001. - 100 с.
3. Бельмер С. В. Целиакия : состояние проблемы / С. В. Бельмер, Т. В. Гасилина, А. А. Коваленко // Лечащий врач. - 2003. - № 6. - С. 69-71.
4. Determination of Anti-Gliadin Antibodies in Serologic Tests for Coeliac Disease / F. G. Chirdo [et al.] // Am. J. Gastroenterol. - 2000. - Vol. 95, N 5. - Р. 508-516.
5. Dickey W. Endomysial Antibody of Coeliac / W. Dickey, D. F. Hughes, A. S. McMillan // Am. J. Gastroenterol. - 2000. - Vol. 95, N 2. - Р. 181-183.
6. MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer / A. Lopez-Vazquez [et al.] // Gut. - 2002. - Vol. 50. - Р. 336-340.
7. Шарипова М. Н. Клинико-эпидемиологическиек и генетические особенности целиакии у детей Казахстана / М. Н. Шарипова // Педиатрия. - 2009. - № 1. - С. 106-108.
Review
For citations:
Danilov A.N., Danilov D.A., Latyshev D.Y., Lobanov Y.F., Pechkina K.G. ATYPICAL GEE’S DISEASE AT CHILDREN: LABORATORY AND TOOL FEATURES. Journal of Siberian Medical Sciences. 2015;(2):11.
Views:
169
Email this article 