The state of ovarian reserve in patients with functional ovarian cysts
https://doi.org/10.31549/2542-1174-2019-1-18-27
Abstract
The study of ovarian reserve indices in patients with functional ovarian cysts (FOC) included 137 patients with infertility and surgical treatment of functional ovarian cysts in history. A retrospective analysis of medical histories was carried out, the indicators of functional ovarian reserve were prospectively determined: serum values of Anti-Müllerian hormone (AMH) and follicle stimulating hormone (FSH), inhibin B, estradiol; volume of ovaries, ovarian antral follicle count (AFC) at sonography on the 2nd–3rd day of the menstrual cycle. The main group (n = 53) consisted of patients who met the Bologna criteria for poor response adopted by the European Society of Human Reproduction and Embryology (ESHRE, 2011); the comparison group consisted of women with a good response to the controlled induction of ovulation (n = 84). Control — conditionally healthy women (n = 15).
The most pronounced decrease in ovarian reserve was revealed in complicated clinical course of FOC (rupture, hemorrhage). Reduction of ovarian reserve indices was observed in patients with repeated invasive interventions on the ovaries, adhesive process of the 3rd and 4th degree, as well as with concomitant inflammatory processes of the pelvic organs in the form of chronic salpingitis.
About the Authors
D. A. Volchenok
Siberian State Medical University
Russian Federation
Russian Federation
Volchenok Daria Aleksandrovna — Graduate Student of the Department of Histology, Embriology and Cytology.
2, Moskovsky Trakt, Tomsk, 634050.
O. A. Tikhonovskaya
Siberian State Medical University
Russian Federation
Russian Federation
Tikhonovskaya Olga Anatolyevna — Dr. Sci. (Med.), Professor of the Department of Obstetrics and Gynecology.
2, Moskovsky Trakt, Tomsk, 634050.
I. A. Petrov
Siberian State Medical University
Russian Federation
Russian Federation
Petrov Ilya Alekseevich — Dr. Sci. (Med.), Professor of the Department of Obstetrics and Gynecology.
2, Moskovsky Trakt, Tomsk, 634050.
S. V. Logvinov
Siberian State Medical University
Russian Federation
Russian Federation
Logvinov Sergey Valentinovich — Dr. Sci. (Med.), Professor, Head of the Department of Histology, Embriology and Cytology.
2, Moskovsky Trakt, Tomsk, 634050.
A. D. Mungalova
Siberian State Medical University
Russian Federation
Russian Federation
Mungalova Anastasia Dmitrievna — Resident of the Department of Obstetrics and Gynecology.
2, Moskovsky Trakt, Tomsk, 634050.
References
1. Gasymova D.M., Rukhlyada N.N. (2017). Clinical and anamnestic characteristics of patients with complications of benign tumors and tumor-like masses of the ovary. Russ. Bull. Obstetrics-Gynecology, 17, 4, 72–77. doi: 10.17116/rosakush201717472-77.
2. Abduljabbar H.S., Bukhari Y.A., Al Hachim E.G. et al. (2015). Review of 244 cases of ovarian cysts. Saudi Med. J., 36, 7, 834–838.
3. Nikogosyan S.O., Kuznetsov V.V., Zagashtokov A.Z. (2017). Emergency and elective surgical management of tumors of the uterine appendages. Obstetrics and Gynecology, 6, 10–17. doi: 10.18565/aig.2017.6.10-6.
4. Karimov Z.D., Ismailova F.I., Khusonkhodzhayeva M.T., Azimova F.M. (2012). Treatment strategy and tactics for ovarian tumor-like lesions in urgent gynecology. Obstetrics and Gynecology, 5, 93–96.
5. Farghaly S.A. (2014). Current diagnosis and management of ovarian cysts. Clin. Exp. Obstet. Gynecol., 41, 6, 609–612.
6. Gasymova D.M., Rukhliada N.N. (2014). State of the female reproductive system after surgery on the ovaries. Transbaikalian Medical Bull., 3, 117–126. In Russ.
7. Medjidova K.K., Alieva Сh.G., Gasanova M.A. et al. (2014). The treatment of the ovarian cysts. Russ. J. Human Reprod., 5, 35–38.
8. Kim J.H., Lee S.M., Lee J.-H. et al. (2014). Successful conservative management of ruptured ovarian cysts with hemoperitoneum in healthy women. PLoSOne, 9, 3: e91171. doi: 10.1371/journal.pone.0091171.
9. Ye X., Yang Y., Sun X. (2015). A retrospective analysis of the effect of salpingectomy on serum antiMüllerian hormone level and ovarian reserve. Am. J. Obstet. Gynecol., 212, 1: 53.e1-53.e10. doi: 10.1016/j.ajog.2014.07.027.
10. Petrov I.A., Tikhonovskaja O.A., Kuprijanova I.I. et al. (2015). The mechanisms of secondary ovarian failure at operations on the pelvic organs (experimental study). Obstetrics, Gynecology and Reproduction, 9, 4, 6–17.
11. Gasparov A.S., Dubinskaya E.D., Titov D.S., Lapteva N.V. (2014). Сlinical value of the ovarian reserve in reproductive function. Obstetrics and Gynecology, 4, 11–16.
Review
For citations:
Volchenok D.A., Tikhonovskaya O.A., Petrov I.A., Logvinov S.V., Mungalova A.D. The state of ovarian reserve in patients with functional ovarian cysts. Journal of Siberian Medical Sciences. 2019;(1):18-27. https://doi.org/10.31549/2542-1174-2019-1-18-27
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