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Journal of Siberian Medical Sciences

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No 5(с) (2016)

13.00.00 ПЕДАГОГИЧЕСКИЕ НАУКИ

1 135
Abstract
Article is devoted to the problem of reforming of the higher medical education regarding change of postgraduate educational system seeing cancellation of internship. As it is known these changes caused ambiguous reaction in society. Results of survey conducted among students of medical and pediatric faculties of NSMU, and also prospective applicants relative to the forthcoming changes are analyzed in the article. As the final decision of this question hasn’t been fixed by normative documents yet, the received results can be of interest to appropriate authorities of health care management. Besides, this article contains digression to the historical background of postgraduate medical education. Materials of research were results of questioning by means of «Google Forms», main normative legal acts on the matter, materials of scientific conferences.
2 286
Abstract
Article is devoted to the 55 anniversary of the first human space flight generally, and in particular - to V. I. Lebedev, the graduate of NSMU, the psychologist working with the first group of astronauts at their preparation for space flight. Also V. I. Lebedev was engaged in scientific work, the part of his researches was carried out in a co-authorship with Ju. A. Gagarin and A. A. Leonov. Materials of research were NSMU archival documents, materials of periodicals publications.
3 191
Abstract
The description and the analysis of various groups of the terms designating color and sound in clinical terminology is presented in the article. Characteristic signs are revealed on which differentiation and classification of these terms are possible. Methods of expression of the colour naming and terms expressing sounds in clinical terminology are investigated.

14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.01.00 КЛИНИЧЕСКАЯ МЕДИЦИНА)

5 152
Abstract
Boron neutron capture therapy (BNCT) is a perspective technique of treatment of malignant tumors. In fact, BNCT is one of methods of binary radiotherapy, referred on selective destruction of cells of a tumor, being of the great clinical interest in neuro-oncology and focused on gliomas therapy, in particular glioblasts. The BNCT technique consists of preliminary accumulation of stable B10 isotope in cells of tumors with the subsequent radiation by the epithermal neutrons focused in fascicle. The idea developed within several decades, some countries began clinical trials and report about positive results. However the reactors generating neutron fascicle has stopped the work seeing the danger of radioactive infection. At Institute of nuclear physics n.a. G. I. Budker of the Siberian Branch of the Russian Academy of Science the tandem accelerator of neutrons with vacuum isolation is created. Now preclinical researches are performed which purpose is to prove that the reached characteristics of fascicle of neutrons generated on it tandem accelerator are optimum for BNCT.
6 195
Abstract
The bronchopulmonary dysplasia (BD) is caused by various reasons: prematurity, respiratory distress syndrome, need for long artificial ventilation of lungs. Disturbances of endocardiac and pulmonary hemodynamics against the congenital heart defects (CHD) and/or hemodynamically significant functioning arterial duct (HSFAD) are capable to influence on the frequency of formation and complication of BD. The analysis of features of BD clinical course at children with disturbances of endocardiac and pulmonary hemodynamics and the «isolated» BD is carried out. Prevalence of severe BD at children with accompanying CHD/HSFAD is defined. Defects with arteriovenous shunting prevail at children with BD and CHD that provokes overload the volume of a small circle of circulation, at this BD is complicated by syndrome of pulmonary hypertensia and chronic heart failure. In this regard this category of patients needs longer respiratory support with usage of higher concentration of oxygen in comparison with group with the «isolated» BD.
7 152
Abstract
The retrospective analysis of 33 medical cases of newborns with critical ductal-dependent congenital heart disease (CHD) is carried out. The following predictors of disease failure are registered: prematurity, chromosomal pathology, CHD combination with other congenital malformations, asphyxia at birth, existence of a multiple-organ-failure syndrome (MOFS) during the first hours after the birth and at presurgical stage, and also comorbide pathology - pneumonia, intraventricular hemorrhage, CHD blood syndrome. Duration of operation should be more than 400 min at operational treatment.
8 168
Abstract
Experimental models of toxic hepatitis caused intragastric and intraperitoneal injection of tetrachlormethane solution. Biochemical and morphological methods of research were applied to assessment of gravity of liver lesion. Toxic hepatitis is confirmed on the basis of the obtained data on both models. The most severe damages of liver arise at intraperitoneal injection of tetrachlormethane. Intragastric injection of tetrachlormethane allows to reduce lethality level (up to 10 %), to avoid disturbance of integrity of integuments and to reduce implication of pain syndrome at animals.
9 170
Abstract
The etiological structure of acute intestinal infections at 118 hospitalized adult patients, residents of Novosibirsk is studied. Along with the standard diagnostic methods, method of polymerase chain reaction (PCR) was used for investigation ofexcrements for identification and differentiation of rotaviruses of A group (HRVA) and C (HRVC) group, norovirus of the second genogroup (HNoV GII) and astroviruses (HAstV) with use of a set of original specific primers. Viral infections are revealed at 30,5 % of patients. Norovirus (64 %) prevailed in structure of viral intestinal infections, the take of rotaviruses made 30,5 %, astroviruses - 5,5 %.
10 172
Abstract
Research objective was the analysis of epidemiological aspects of fractures in the condylar process of mandible angle (CPMA) and methods of their treatment in maxillofacial surgery unit at SBHE NR"Novosibirsk State Regional Clinical Hospital«. Retrospective research by studying of patients’ case with fractures of mandibular articular process is conducted. As a result the research revealed high percent of patients with CPMA fractures. Splinting and osteometallosynthesis remain the main methods of treatment. The mandible immobilization with external fixing elements prevails over operative methods of treatment of CPMA fractures.
11 96
Abstract
Article is devoted to the matter concerning development of clottage of central retinal vein (CCRV) with definition of influence of various etiological factors. The role of influence of some factors on CCRV development is considered in the article, and also comparison of disease at patients of various age and with different etiological factors is carried out. The tendency to changes of distribution in different groups of etiological factors is revealed according to results of the literature review. Two surveys of CCRV clinical cases of are presented.
12 154
Abstract
This article is devoted to subject of metabolic syndrome at dermatologic patients. The clinical case of the patient with psoriasis, stretch marks and metabolic syndrome is presented in the research. Authors of the article concluded that the comorbidity of metabolic syndrome and psoriasis exert negative impact on the state of the patient, influence tactics of doctor, enlarge hospitalization terms.
13 116
Abstract
The analysis of results of multislice computer tomography (MSCT) and functional tests of 106 patients with various pulmonary diseases is submitted. Research objective is to estimate accuracy of measurements of pulmonary function when using three-dimensional reconstruction of MSCT images in comparison with standard testings of respiratory function. Total lung capacity was calculated on three-dimensional MSCT images. Vital lung capacity and forced expiratory volumen per 1 second were measured by spirometry. The analysis of obtained information is carried out, positive correlation between the assumed total lung capacity and measured values of total lung capacity is revealed. Three-dimensional volume modeling of MSCT images can be used for assessment of respiratory function.
14 141
Abstract
Tactics of prenatal care and labors significantly depends on the fetus mass and amount of amniotic waters. The growth inhibition, fetus macrosomia, small and hydramnion are pathological markers at pregnancy and often lead to complications of the intranatal period. A research objective was determination of efficiency of ultrasonic methods of determination of fetus mass and volume of amniotic waters. The error of calculation of fetus mass and amount of amniotic waters by standard ultrasonic methods exceeds 10 % that defined the need of their modification by the complex analysis of ultrasonic criteria and mathematical modeling.
15 119
Abstract
Epidemiological and clinical laboratory indicators at the 31 adult Novosibirsk residents suffering from acute viral hepatitis C are studied. Patients of young age and women prevailed. Parenteral interventions prevailed In epidemiological anamnesis. Icteric medium-weight form of illness dominated. Variability of indicators of cytolysis and cholestasia is registered. The importance of RNA identification of HCV is shown for diagnosis verification by the PCR method at small informational content of definition of HCV antibodies in EIA (33 %). High efficiency of therapy by interferon drugs within 12 weeks (92,9 %) is established.
16 119
Abstract
The objective of research is performing the analysis of epidemiological situation on scabies in Novosibirsk during 2013-2015. The modern situation on scabies case rate is characterized by a tendency to depression of officially recorded indicators. Basic layer of the patients are the people with registration. Women are ill more often among them. The main age group consists of children of 2-14 years. The leading position on scabies case rate in Novosibirsk is taken by Kalininskiy district.
17 121
Abstract
Dismaturity of neuronal system of ureter is frequently a reason of primary obstructive megaureter and which formation can be completed within the first year of life. Therefore radical surgery in the first months of life of the child isn’t advisable. On the basis of Novosibirsk CCCH N1 a drainage of ureter was applied at patients with primary obstructive megaureter by pyeloureterostomy method. Results of verification servey at the age of the 1st year showed normalization of a passage on ureter in 75 % percent of cases.

14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.03.00 МЕДИКО-БИОЛОГИЧЕСКИЕ НАУКИ)

18 138
Abstract
Argentiferous porous composition is developed in FSBSE «SRICEX» and research of efficiency assessment of sorbent is conducted concerning the developed endotoxins and the most microbial flora (Salmonella enteritidis) after 1, 3, 6, 12 hours at intraperitoneal introduction of centrifugate by criterion of mortality and change of internals mass (lien, liver) of laboratory mice. Positive dynamics of change of mass of lien and liver at exposition time augmentation is revealed. The survival of animals after centrifugate introduction (exposition of 6 and 12 hours) made 100 %.

14.00.00 МЕДИЦИНСКИЕ НАУКИ (14.04.00 ФАРМАЦЕВТИЧЕСКИЕ НАУКИ)

4 136
Abstract
Research of change of vitamin E content in wheat grains in the course of their sprouting is conducted. The technique of quantitative determination of tocopherols content value in vegetable raw materials on absorption of UF-radiation with wavelength of 292 nanometers is fulfilled. It is shown that change of maintenance of tocopherol in grains is caused by physiological processes proceeding in initial stage of ontogenesis of plant body and it is established that the maximum content of vitamin E is reached 24 hours later after the beginning of seed sprouting process.


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ISSN 2542-1174 (Print)